Publications by authors named "Tomoaki Kawamoto"
Article Synopsis
- Scientists are working on new ways to test cancer drugs by looking at how they affect tumor cells and how well they get inside the tissues.
- They created a special setup using a customized plate that separates the tumor cells, allowing them to treat only part of the tumor while monitoring its growth.
- By using colored substances to check if the sections are working, they confirmed their method successfully isolated the treatment area and could measure how the drug affected the cells’ growth.
Cisplatin (CDDP) is a useful drug for the treatment of malignant solid tumors of the head and neck. Because CDDP includes the heavy metal platinum as a component, it is thought metallothionein (MT) may be involved in CDDP-resistance. However, functional differences between the four MT isoforms (MT-I, II, III and IV) remain unclear.
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