Publications by authors named "Tomoaki Hamano"

Purpose: There have been several reports of central nervous system impairments associated with severe coronavirus disease 2019 (COVID-19) infection on head magnetic resonance imaging and angiography (MRI/A). However, head MRI/A is rarely performed in mild cases, and there have been few reports on intracranial changes after COVID-19 infection in these cases. Here, we report a comparative examination of the findings seen in common head MRI/A sequences in mild cases of COVID-19.

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Article Synopsis
  • The study investigated the prevalence and factors related to enlarged perivascular spaces (EPVS) in healthy individuals in their 40s, focusing on two locations: basal ganglia (EPVS-BG) and centrum semiovale (EPVS-CSO).
  • Out of 5000 participants, 1720 were analyzed, revealing a prevalence of 7.7% for EPVS-BG and 9.2% for EPVS-CSO, with certain risk factors like age, smoking history, and hypertension linked to EPVS-BG.
  • The findings suggest that while EPVS can occur in younger individuals, their prevalence is lower compared to older populations, indicating potential early signs of atherosclerosis and cerebral amyloid
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This study aimed to determine the prevalence and risk factors for brain white matter changes in normal young and middle-aged participants who underwent Brain Dock (brain screening). We analyzed 5,000 consecutive healthy participants from the Brain Dock registry between August to December 2018. Age, sex, body mass index (BMI), medical history, deep subcortical white matter high intensity (DSWMH), periventricular high intensity (PVH), and enlargement of perivascular space (EPVS) were investigated in relation to age.

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