Publications by authors named "Tomo Suzuki"
Article Synopsis
- Higher levels of hope in patients with chronic kidney disease (CKD) are linked to lower distress from fluid and dietary restrictions, especially in the first year of dialysis.
- The study included 444 CKD patients undergoing various types of dialysis in Japan and measured hope using a specific health-related hope scale.
- While increased hope positively affected patient distress levels at one year, it showed no significant effect on distress at the two-year mark, suggesting that hope may have a short-term impact on managing restrictions.
The prognosis of anti-glomerular basement membrane (anti-GBM) nephritis, often accompanied by the presence of antineutrophil cytoplasmic antibodies (ANCA), is poor, and even with aggressive therapeutic approaches, kidney replacement therapy (KRT) is typically required. Here, we present a case of necrotizing crescentic glomerulonephritis in a patient double-seropositive for anti-GBM antibodies and ANCA who successfully achieved dialysis independence following aggressive treatment, including avacopan. The patient was a 77-year-old woman with rapidly progressive glomerulonephritis and double seropositivity for myeloperoxidase-ANCA and anti-GBM antibodies.
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- * A specific bacteria, which is common in the eye, decreases in abundance as we age and can behave as both an infectious agent and an immune trigger.
- * The review focuses on how this bacteria contributes to various eye inflammations, affecting diagnosis and treatment strategies.
LCPS-1, a cell wall polysaccharide (CWPS), is bound to the cell wall of the probiotic Lacticaseibacillus paracasei (formerly known as Lactobacillus casei) strain Shirota (LcS). Generally, the role of CWPS in the viability and survivability of bacteria is yet to be fully understood. This study aimed to elucidate the role of LCPS-1 in the viability and survivability of LcS.
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- - A 39-year-old woman with Gitelman syndrome faced challenges conceiving and underwent in vitro fertilization-embryo transfer (IVF-ET) due to her hypokalemia, which was critically low at 2.2 mEq/L.
- - Throughout the pregnancy, her potassium levels were closely monitored, leading to hospitalization and an increase in potassium replacement as her levels dropped to 2.5 mEq/L at 8 weeks but improved to 3.0 mEq/L by 11 weeks.
- - The pregnancy resulted in a healthy vaginal delivery at 38 weeks, with the patient's potassium levels remaining stable postpartum, and genetic testing confirmed her condition as consistent with Gitelman syndrome.
Background: Gastrointestinal transit (GIT) is influenced by factors including diet, medications, genetics, and gut microbiota, with slow GIT potentially indicating a functional disorder linked to conditions, such as constipation. Although GIT studies have utilized various animal models, few effectively model spontaneous slow GIT.
Aims: We aimed to characterize the GIT phenotype of CFP/Yit (CFP), an inbred mouse strain with suggested slow GIT.
Relapsing Peritoneal Dialysis-Associated Peritonitis due to : A Case Report.
Case Rep Nephrol Dial
January 2024
Introduction: The genus, encompassing gram-positive coccoid actinobacteria belonging to the Micrococcaceae family, has recently been discovered residing on the human skin and oral flora. Reports of -associated infections in humans have been scarce. Herein, we present the first case of relapsing peritoneal dialysis (PD)-associated peritonitis caused by .
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- Pediatric blepharokeratoconjunctivitis (PBKC) is a serious, underrecognized eye disease in kids that leads to inflammation of the eyelid and eye surface, potentially threatening vision.* -
- The study aimed to create a unified name, definition, and diagnostic criteria for PBKC, using expert input through surveys and online meetings over almost a year.* -
- A consensus was achieved, providing a clear definition and guidelines for diagnosing PBKC that emphasizes its chronic nature and specific symptoms across various eye areas.*
Background: Basic health literacy and trust in physicians can influence medication adherence in patients receiving dialysis. However, how high-order health literacy is associated with medication adherence and how trust in physicians mediates this association remain unclear. We assessed the inter-relationships between health literacy, trust in physicians, and medication adherence.
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- * A renal biopsy indicated thrombotic microangiopathy (TMA), characterized by clots in small blood vessels, while cardiac tests revealed significant artery narrowing and heart muscle disease.
- * High levels of amphetamines and methamphetamines were detected in his blood, suggesting a potential link between methamphetamine use and the observed organ dysfunction and kidney damage.
Some of obstetrical complications such as unexplained pregnancy loss and preeclampsia (PE) are associated with maternal-fetal immune abnormalities, leading to uteroplacental dysfunction, insufficient fetal immune tolerance, or fetal rejection. Immunosuppressants with calcineurin inhibitors could be useful for the prevention of these complications by modulating the cellular immune balance by directly inhibiting activated T-helper (Th) 1 and natural killer (NK)/NKT cells. We present our experience with the immunosuppressant tacrolimus in five pregnant women who had a previous pregnancy history of unexplained or preeclamptic stillbirth.
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- This observational study evaluated the outcomes of peritoneal dialysis (PD) catheter placement in Japan to see if they align with the International Society for Peritoneal Dialysis guidelines.
- The study tracked 409 adult patients who underwent PD catheter placement, finding a low rate of catheter patency failure (6.2%) and a technique failure rate of 15.3% after 12 months.
- Factors influencing technique failure included lower serum albumin levels and type of catheter used, while diabetes increased the risk of perioperative infections; however, overall complications met ISPD audit standards.
Article Synopsis
- The study aimed to find a simpler way to collect and analyze breast milk for the presence of biologics, which are drugs that may be used by nursing mothers.
- Researchers used a method involving dried filter paper samples to measure drug concentrations over a 28-day period, ensuring accurate results.
- The findings suggest that this method is reliable and can help improve medication management for lactating women who need biologic therapies.
In this rare case of infection-related cryoglobulinemic glomerulonephritis with infective endocarditis, a 78-year-old male presented with an acute onset of fever and rapidly progressive glomerulonephritis. His blood culture results were positive for , and transesophageal echocardiography showed vegetation. He was diagnosed with endocarditis.
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- Acute kidney injury and chronic kidney disease after cardiac surgery can lead to serious health risks, and the effects of intraoperative hemodialysis (IHD) on renal function post-surgery are unclear.
- A study involving patients with severe non-dialysis-dependent chronic kidney disease (CKD-NDD) assessed the outcomes of IHD during elective open-heart surgery, comparing patients who received IHD to those who did not.
- Results showed no significant differences in 90-day mortality or renal replacement therapy rates overall, but patients with CKD G4 who had IHD had notably lower rates of needing renal replacement therapy 30 days post-surgery.