Publications by authors named "Tomo Ishisaka"
Objectives: Injury to the external branch of the superior laryngeal nerve (EBSLN) causes low-pitch voice and voice fatigue, particularly in female subjects, and available treatments are limited. Here, we assess a novel surgical procedure to restore a high-tone voice: ansa cervicalis to EBSLN anastomosis (A-E anastomosis).
Methods: Between November 2012 and April 2022, 13 patients (12 female) underwent unilateral EBSLN resection and A-E anastomosis, while 20 (16 female) underwent EBSLN resection during thyroid surgery.
Article Synopsis
- Researchers studied five cases of medullary thyroid carcinoma (MTC) that displayed unique papillary-like nuclear features not previously described in the literature.
- The study involved detailed cytological analysis and evaluations of tumor markers, highlighting characteristics such as chromatin patterns, cellular features, and specific mutations in the patients.
- The findings suggest that the presence of these papillary-like nuclear features may indicate a higher-grade MTC, potentially serving as important prognostic markers for better diagnosis and treatment.
Microfluidics is applied in biotechnology research via the creation of microfluidic channels and reaction vessels. Filters are considered to be able to simulate microfluidics. A typical example is the cell culture insert, which comprises two vessels connected by a filter.
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- Recurrent laryngeal nerve (RLN) injury is a serious risk during thyroid surgery, and intraoperative nerve monitoring (IONM) is commonly used to prevent this complication.
- This study details the first successful use of continuous IONM (CIONM) during minimally invasive video-assisted endocrine neck surgery (VANS), applying it to 22 patients over a two-year period.
- The results showed no RLN injuries in patients undergoing VANS with CIONM, although the method extended surgery time by about 30 minutes due to its technical challenges. Future research is needed to compare CIONM's effectiveness with traditional intermittent IONM.