Publications by authors named "Tomiris Kusainova"
Article Synopsis
- Multidrug-resistant strains, particularly those linked to farm animals, are a growing concern for human health due to their ability to cause severe intestinal and extraintestinal diseases.
- This study focuses on APEC 36, a strain isolated from a chicken with a serious infection, analyzing its genome and finding it has multiple antibiotic resistance mechanisms, mainly antibiotic efflux.
- APEC 36 also contains unique genetic traits, such as a rare beta-lactamase variant and genes linked to toxins and iron uptake, indicating that it could pose significant threats to human health.
In recent years, ultrafast liquid chromatography/mass spectrometry methods have been extensively developed for the use in proteome profiling in biochemical studies. These methods are intended for express monitoring of cell response to biotic stimuli and elucidation of correlation of molecular changes with biological processes and phenotypical changes. New technologies, including the use of nanomaterials, are actively introduced to increase agricultural production.
View Article and Find Full Text PDFVarious external and internal factors damaging DNA constantly disrupt the stability of the genome. Cells use numerous dedicated DNA repair systems to detect damage and restore genomic integrity in a timely manner. Ribonucleotide reductase (RNR) is a key enzyme providing dNTPs for DNA repair.
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