NIPT with the analysis of all chromosomes for aneuploidy screening. Chromosomal microarray 750K, routine karyotyping and Whole-exome sequencing and Sanger sequencing were used for the analysis of the clinical situation Sonographic fetal abnormalities were accompanied by the placental mosaicism (trisomy 16), fetal partial uniparental disomy of the short arm of chromosome 16. NIPT with the analysis of all chromosomes is a powerful tool to identify placental mosaicism, which in turn can manifest itself as nonspecific abnormalities in biochemical markers, placental dysfunction, growth retardation, fetal malformations, preterm birth, etc.
View Article and Find Full Text PDFChir Narzadow Ruchu Ortop Pol
May 2008
Tibia ankle fractures and traumatic injuries of the ankle-tibia joint area are one of the most intractable problems in orthopedic and traumatic surgery. Because of the displacement of these fractures they require precise opening of the joint surface area to undertake the early repositioning in order to gain eficient walk. The objective of this paper was to evaluate and compare the final results of nonoperative and operative treament methods, specificlly the two most common prognosis values of tibia ankle fracture clasifications by Danis-Weber and Lauge-Hansen.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
May 2000
Background: As the population ages, a greater demand for long-term care services and, in particular, nursing homes is expected. Policy analysts continue to search for alternative, less costly forms of care for the elderly and have attempted to develop programs to delay or prevent nursing-home entry. Health care administrators require information for planning the future demand for nursing-home services.
View Article and Find Full Text PDFObjectives: This study profiled health care utilization by disabled and nondisabled individuals in the Canadian province of Manitoba to evaluate the association between health care utilization and disability.
Methods: Age-standardized annualized utilization rates were calculated according to sex using longitudinal data on individual encounters with the Manitoba health care system from 1983 to 1990. Associations between severity of disability, number of prior chronic conditions, and prospective utilization were examined using multivariate regressions.
Most studies of the relationship between socioeconomic status (SES) and health have concentrated on disparities between the richest and poorest men; few studies have examined such relationships for women due to difficulties in measuring SES for women. For the present study, data collected from Canadian Public Service middle and senior managers provided an opportunity to examine associations between SES and health within the upper end of the SES spectrum for both genders, since women managers can be assumed to have a relatively high SES. Demographic, health and lifestyle characteristics are compared for middle and senior managers for each gender separately to determine whether women experience the health benefits associated with higher SES that have been previously observed for men.
View Article and Find Full Text PDFHelical CT provides a rapidly acquired, accurately registered, two-dimensional data set during the phase of maximum vascular and parenchymal enhancement. The z-axis can be covered by using either a single acquisition, single breath-hold technique or by using multiple helical groups with intergroup delays for the patient's breathing. The latter approach, called variable-mode helical CT, allows large z-axis coverage of more than one anatomic region during injection of a single bolus of contrast material.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
September 1994
Purpose: To determine whether magnetization transfer contrast can differentiate acute from chronic lesions in multiple sclerosis.
Methods: Thirteen patients with multiple sclerosis and eight healthy patients were studied with MR using a 0.1-T system.
JPEN J Parenter Enteral Nutr
November 1994
The purpose of our study was to report our experience with percutaneous placement of intravascular stents to relieve venous occlusion in patients with acute superior vena cava syndrome resulting from benign etiologies. Six patients ranging in age from 39 to 66 years received thrombolysis followed by placement of stents within the superior vena cava or received stent placement alone as emergency treatment for symptoms of acute superior vena cava obstruction. Treatment was successful in all patients, with establishment of a patent lumen angiographically, and patients experienced prompt symptomatic relief.
View Article and Find Full Text PDFChir Narzadow Ruchu Ortop Pol
October 1995
The mode of treatment used in 6 cases of combined supracondylar fracture of the humerus and ipsilateral forearm fracture is presented. Results were rated good, fair and poor according to both functional and radiological assessments. Three cases were good and 3 fair.
View Article and Find Full Text PDFThere is widespread interest in disparities in health status across income groups and other classifications of socioeconomic status. In Canada, as in many other countries, there is considerable evidence showing such disparities. This study reports an analysis of male mortality at ages 65 to 74 in relation to socioeconomic characteristics, specifically employment and self-employment earnings histories during the 10 to 20 years prior to age 65, marital status, disability, and age at retirement.
View Article and Find Full Text PDFCT imaging of traumatic aortic rupture has been both advocated and disparaged in the current literature as a reliable diagnostic modality. In a retrospective review of blunt chest trauma patients at our institution evaluated by both thoracic CT and arteriography, we found a 17% false negative rate and a 39% false positive rate. Although we feel CT is not sufficiently sensitive at present to evaluate traumatic rupture of the aorta directly, it is an invaluable adjunctive imaging modality for stable blunt chest trauma patients with equivocal chest radiographs or arteriograms.
View Article and Find Full Text PDFThis paper examines the association between hypertension and demographic, genetic, personal, and socio-economic risk factors. Logistic regression models were fitted to data from the 1978-79 Canada Health Survey. The analysis showed that age, sex, genetic history, and body mass index were important factors in predicting high blood pressure.
View Article and Find Full Text PDFSeveral indicators of the presence of high blood pressure, taken from different parts of Canada Health Survey data, are compared at the individual respondent level to determine their consistency and their usefulness, alone or in combination, in measuring the prevalence of hypertension. The results demonstrate some systematic and substantial discrepancies among various high blood pressure indicators derived from questionnaire data, and between questionnaire data and physically measured blood pressure status.
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