Publications by authors named "Tome Lopes"

Introduction: Renal cell carcinoma (RCC) often develops a tumor thrombus extending into the inferior vena cava (IVC). Radical nephrectomy with IVC thrombectomy is the standard treatment, although prognostic factors are yet to be properly established.

Objectives: The objectives of this study were to review the clinicopathological features of surgically treated patients with RCC and IVC thrombus and to investigate potential prognostic factors.

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Background: Circulating tumor cells (CTCs) may be the missing renal cell carcinoma (RCC) biomarker. No-touch (NT) resection has shown benefit in several tumors.

Methods: A randomized controlled trial comparing CTC and circulating mesenchymal cell (CMC) release in no-touch (NT) vs.

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Renal cell carcinoma (RCC) presents as metastatic disease in one third of cases. Research on circulating tumor cells (CTCs) and liquid biopsies is improving the understanding of RCC biology and metastases formation. However, a standardized, sensitive, specific, and cost-effective CTC detection technique is lacking.

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Circulating tumor cells (CTCs) have a potential role as the missing renal cell carcinoma (RCC) biomarker. However, the available evidence is limited, and detection methods lack standardization, hindering clinical use. We performed a systematic review on CTC enrichment and detection methods, and its role as a biomarker in RCC.

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Bladder cancer (BC), the most frequent malignancy of the urinary system, is ranked the sixth most prevalent cancer worldwide. Of all newly diagnosed patients with BC, 70-75% will present disease confined to the mucosa or submucosa, the non-muscle-invasive BC (NMIBC) subtype. Of those, approximately 70% will recur after transurethral resection (TUR).

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Background/aims: Sacral neuromodulation (SNM) is a well-established treatment in several urinary and bowel dysfunctions, nevertheless its role on sexual dysfunction remains unclear. We evaluate the impact of SNM on sexual function and its association with age at SNM, functional diagnosis and post-void residual urine (PVR) before SNM.

Methods: Patients who had SNM were retrospectively analyzed.

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Background/aims: Laparoscopy is a widespread surgical approach for many urological conditions. Achieving prof-ciency in laparoscopic surgery requires considerable effort due to the steep learning curve. Several residency programs include standardized laparoscopic training periods in their curricula.

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Objective: Low-intensity shock-wave treatment (LiSWT) is a therapy for erectile dysfunction (ED) with good results reported in the literature. The aim of this study was to evaluate the results of LiSWT on patients treated for ED and the influence of ED duration in treatment outcomes.

Material And Methods: We performed an open-label single-arm prospective study of patients treated with LiSWT for ED.

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Traumatic ureteral injuries are rare and account for less than 1% of all urological traumas. Associated abdominal injuries are almost always present. We present a rare case of isolated shotgun injury to the ureter where clinical suspicion was of paramount importance.

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Objective: To present a case of a bilateral synchronous testicular seminoma in a young male clinical stage IIB.

Material And Method: A 37 years old man presented a bilateral testicular mass with elevated tumoral markers. Histology of frozen section revealed bilateral seminoma and bilateral radical orchiectomy was performed.

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Introduction: Urorectal fistula (URF) is a devastating complication of pelvic cancer treatments and a surgical challenge for the reconstructive surgeon. We report a series of male patients with URF resulting from pelvic cancer treatments, specifically prostate (PCa), bladder (BCa), and rectal cancer (RCa), and explore the differences and impact on outcomes between purely surgical and non-surgical treatment modalities.

Methods: Between October 2008 and June 2015, 15 male patients, aged 59-78 years (mean 67), with URF induced by pelvic cancer treatments were identified in our institutions.

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Pelvic fracture urethral injuries (PFUI) are devastating lesions that lead to fibrosis and urethral disruption, which result in recurrent strictures, urinary incontinence, fistulae, and even erectile dysfunction, representing a management problem for the urologist. Magnetic resonance imaging (MRI) may be a valuable tool in establishing or confirming the diagnosis by providing detailed anatomy and estimating disease extent. We present a comprehensive review of the current literature on the role of MRI on diagnostic evaluation and surgical management of patients with PFUI.

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Objective: To present a case of a Hutch bladder diverticulum containing the ureteral opening.

Material And Methods: An 83-year-old man presented a giant bladder diverticulum causing obstructive azotemia due to bilateral ureteral compression. Endoscopy revealed an unusual and potentially harmful anatomical alteration: the left ureteral orifice was inside in the diverticulum.

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Objective: To present an updated description of the relation between Crohn's disease (CD) and Urolithiasis.

Patients And Methods: A literature search for English-language original and review articles was conducted in Medline, Embase, and Cochrane databases in the month of December 2014 for papers either published or e-published up to that date, addressing the association between CD and urolithiasis as its consequence. All articles published in English language were selected for screening based on the following search terms: "CD," "renal calculus," "IBD," and "urolithiasis.

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Article Synopsis
  • The study aimed to determine if the Vienna nomogram improves cancer detection rates in prostate biopsies compared to a standard 10-core biopsy method.
  • A total of 456 men were enrolled and randomized into two groups for biopsy, with results indicating no significant difference in cancer detection rates between the Vienna nomogram group (42.6%) and the 10-core group (38.4%).
  • The findings suggest that using the Vienna nomogram does not enhance cancer detection effectiveness, highlighting the need for further research with larger sample sizes.
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Introduction: Peyronie's disease, a fibrotic disorder of the tunica albuginea of the penis, has been associated with penile shortening and some degree of erectile dysfunction. It affects patient's quality of life, leading to severe psychological, mental, and physical stress. Penile deformation hampers sexual life leading to depression, lack of sexual confidence, loss of sexual function and performance anxiety.

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Malignant priapism is a definition invented in 1938 by Peacock, defined as a persistent erection, not related with sexual activity, caused by cavernous sinus and associated venous systems invasion with malignant cells. Penile secondary lesions are rare entities. Primary locations are usually the pelvic cavity organs, namely the prostate and the bladder as the most common ones.

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Introduction: Sexual intercourse is often a reason for an emergency room visit because of urinary tract traumas.

Aim: To present an organized description of the most common urological emergencies during sexual intercourse and its management in emergency settings.

Methods: We reviewed the most common urological emergencies that occurred related to sexual intercourse.

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We present a case report of a 17-year-old patient with a large renal mass that was detected on a computed tomography scan during investigation for secondary hypertension. Radical nephrectomy was performed and the morphologic and immunocytochemical findings were compatible with a diagnosis of monophasic synovial sarcoma of the kidney. A cytogenetic search for t(X;18) translocation was performed, which was negative.

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Purpose: The study focused on the use of balloon or telescopic/serial dilation methods in percutaneous nephrolithotomy (PCNL) in the Global PCNL Study.

Patients And Methods: Centers worldwide provided data from consecutive patients who were treated with PCNL during a 1-year period. Tract dilation was performed using a balloon or telescopic/serial dilator.

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Introduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in well-selected patients to minimize physical disfigurement and consequently maximize quality of life.

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