The four Ps of patient experience: A new strategic framework informed by theory and practice.

This article proposes a new strategic framework to assist healthcare organizations in achieving great patient experiences in the healthcare setting. We synthesize models of practice and literature relevant to the patient experience in order to propose the four Ps of patient experience. Key levers used in this model are: (a) trained autonomous physicians, (b) multidisciplinary partners, (c) alternative places of care delivery matched to patient conditions and needs, and (d) standardized yet flexible processes.

Identification of a Coding Sequence and Structure Modeling of a Glycine-Rich RNA-Binding Protein (CmGRP1) from L.

The family of glycine-rich plant proteins (GRPs) is a large and complex group of proteins that share, as a common feature, the presence of glycine-rich domains arranged in (Gly)n-X repeats that are suggested to be involved in protein-protein interactions, RNA binding, and nucleolar targeting. These proteins are implicated in several independent physiological processes. Some are components of cell walls of many higher plants, while others are involved in molecular responses to environmental stress, and mediated by post-transcriptional regulatory mechanisms.

Theoretical and analytical characterization of a flow-through permeation liquid membrane with controlled flux for metal speciation measurements.

Speciation measurements with the permeation liquid membrane (PLM) technology require necessarily a good control of the flux of the analyte. In this perspective, a PLM-based multichannel flow-through cell has been designed. The first objective of this study has been to adapt the classical Levich model commonly used for electrochemical flow devices to the characteristic geometry of the PLM cell.

Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea.

A major transport function of the human intestine involves the absorption of chloride in exchange for bicarbonate. We have studied a recessively inherited defect of this exchange, congenital chloride diarrhoea (CLD; MIM 214700). The clinical presentation of CLD is a lifetime, potentially fatal diarrhoea with a high chloride content.

[Alpha 1-antitrypsin as an endogenous marker of protein-losing enteropathies].

A novelty of the present studies is the use of alpha 1-antitrypsin (A-1--AT) as an endogenous marker of enteric protein loss. Enteric clearance of alpha 1-antitrypsin was determined in 10 patients with the symptoms of PLE, and in 6 healthy individuals. Alpha 1-Antitrypsin concentration has been assayed in single, random samples of feces collected from 42 patients and 12 healthy individuals (normal values: 1.

Fructosamine in human and bovine semen.

We detected the presence of fructosamine in human and bovine semen. In seminal plasma of healthy normozoospermic men (N = 17) fructosamine was found in 53% of the cases (fru+). In fru+ semen samples the concentration of fructosamine was (mean +/- S.

[Indicators of the identity of aspirates from the oral cavity of newborn infants and the amniotic fluid: pH, protein levels and the activity of trypsin inhibitor].

The aim of the study was to establish the biochemical identity as regards pH, protein content and trypsin inhibitor activity between the aspirate from the various sites of the newborn oral cavity and the amniotic fluid. It has been found that only correctly collected aspirate from the oral cavity without any admixture of the subepiglottic or gastric content is identical with amniotic fluid. Measurement of trypsin inhibitor activity in the improperly collected aspirate with pH below 5 must not be performed.

[Activity and molecular form of intestinal gamma-glutamyltransferase (GGT) EC 2.3.2.2. in celiac disease].

It has been shown that GGT activity in the duodenal biopsy homogenates of the children with coeliac disease (n-10) in remission (1 to 3 years of gluten-free diet) is lower than in those with other gastrointestinal tract diseases (n-6). In children with coeliac disease after gluten challenge (1 g of gluten) kg BW for 3 to 6 months) the GGT activity decreased fourfold (n-10). After a few months of gluten challenge there was in coeliac children (n-5) a marked predominance of GGT without sialic acid (the asialic GGT).

[Intestinal arginase in the phylogenetic development of animals].

The activity of intestinal arginase was studied in 31 species belonging to the types Annelides, Arthropoda and Chordata. Large variations of the enzyme activity were tested. The differences were of 2 orders of magnitude--100 times.

[Multi-indicator biochemical and clinical evaluation of occupational exposure of workers in the petrochemical industry. II. Results of the search for early clinico-biochemical signs of exposure to toxic substances present in the petrochemical industry. Analysis of the results of 5-year epidemiological studies].

The activities of GGT (EC 2.3.2.

[Multi-indicators in the biochemical and clinical evaluation of exposure of workers in the petrochemical industry. I. Preliminary epidemiologic screening studies].

Eleven non-routine biochemical and clinical indicators (selected of 26 preliminarily estimated) in Petrochemical Plant workers and in controls, localized in an increasing distance from the Plant (3-18-40 km), have been measured. Even in the 3 km distance, no effects of the Petrochemical Plant have been found. All the exposed groups exhibited changes in enzymes GGT and TA.

Studies on L-arginase in developing rat small intestine, brain, and kidney. II. Effect of hydrocortisone and thyroxine.

The influences of hydrocortisone and thyroxine on the developmental changes of arginase activity in intestine, kidney, and brain of suckling rats were studied. A single injection of hydrocortisone (50 mg/kg) into rats aged 9 days evoked premature increase of jejunal arginase activity due to precocious formation of arginase A4. Arginase A4 can be detected about 48 hr after hydrocortisone injection, whereas in intact rats the enzyme appears in the intestinal mucosa on the 19th-21st days of postnatal life.

Studies on L-arginase in developing rat small intestine, brain, and kidney. I. Ontogenic evolution of arginase isoenzymes.

The adult patterns of arginase isoenzymes in rat intestine, kidney, and brain are nearly identical and consist of two forms, cationic A1 and anionic A4. In this paper, the organ-specific maturation of the enzyme equipment in these tissues is reported. The activity of arginase in all tissues studied could be detected on the 13th to 16th days of gestation.

A simple quantitative micromethod of arginase assay in blood spots dried on filter paper.

An accurate, precise and sensitive method has been developed for measurement of arginase activity in erythrocytes in dried blood spots. The assay is based on colorimetric measurement of ornithine produced by enzymatic hydrolysis of L-arginine. Only 10 microliter of capillary blood collected on filter paper are required.