Actigraphic monitoring of activity and rest in schizophrenic patients treated with olanzapine or risperidone.

Metabolic disturbances are a growing concern for the treatment of schizophrenia. As decreased activity and poor sleep quality are risk factors for metabolic disturbances, we investigated the activity and sleep patterns of schizophrenic patients using actigraphy. Seventy-three patients with schizophrenia spectrum disorder (mean age 29.

[Subjective and objective evaluation of olanzapine treatment in schizophrenia].

Aim: The study was to evaluate objectively (by a physician) and subjectively (by the patients) the efficacy of 12-months olanzapine treatment of schizophrenic out-patients.

Method: Olanzapine treatment was either initiated or patients were switched from other antipsychotics to olanzapine. Patients' subjective evaluation with the use of SWN and DAI scales was compared with physicians' objective evaluation with the use of PANSS, CDS and CGI scales.