Changes in the concentration of sHLA-I and selected cytokines in pregnancy complicated by antiphospholipid syndrome.

Objectives: To compare the serum concentrations of the selected cytokines from subsequent trimesters of antiphospholipid syndrome complicated pregnancies.

Material And Methods: This study included 43 pregnant women (23 patients diagnosed with antiphospholipid syndrome and 20 controls). IL-2R, IL-4, IL-10, INF-gamma, TNF-alpha, and class I sHLA concentrations were analyzed by ELISA in the 1st, 2nd and 3rd trimester

Results: INF-gamma levels were below the method detection threshold and therefore were not included in the final analysis.

Assessment of the female fetal DNA concentration in the plasma of the pregnant women as preeclampsia indicator--preliminary report.

Objectives: This research was designed to analyze the presence of fetal female DNA, expressed in copy number, in the plasma of the pregnant woman with preeclampsia-complicated pregnancy.

Study Design: Twenty-four pregnant women with female fetuses identified by means of ultrasound scanning were enrolled in this pilot study. The study group consisted of 12 pregnant women with symptoms of preeclampsia, with 12 healthy women, matched for gestational age, as controls.

The analysis of the correlation between extracellular fetal DNA concentration in maternal circulation and severity of preeclampsia.

Introduction: Increased fetal DNA in maternal plasma has been reported in pregnancies complicated by preeclampsia. Fetal DNA may by liberated from fetal or placental cells during apoptosis. The aim of the study is the estimation of the correlation between clinical and biochemical characteristics of preeclampsia and the concentration of fetal DNA in maternal circulation.

Antigens HLA-G, sHLA- G and sHLA- class I in reproductive failure.

It can be supposed that relation between HLA-G polymorphism and sHLA-G protein expression are associated with successful embryo implantation and pregnancy maintenance. The aim of the study was the estimation specific differences in expression of sHLA-G and sHLA- class I antigens in women with reproductive failure in comparison with fertile women. The study sample enrolled 80 women, divided into 2 groups.

[Pregnancy, labour and puerperium in patient after replacement of the descending thoracic aorta with a synthetic graft for aneurysm].

Aortic aneurysms occurs very rarely in young women. They usually accompany congenital heart diseases, Marfan's syndrome, bicuspid aortic valve and coarctation. What is more, they may be the consequence of syphilis and trauma, however less frequently.

[Anomalies of the tongue in the fetus and neonate].

This work reviews the literature on the development of the tongue and its function during fetal life. Research on fetal behavior in general and functioning of structures of the skull, face and neck during fetal life in particular was very difficult, not to say impossible, until the present era of ultrasonography with flow (color Doppler and power Doppler), as well as 3D and 4D imaging. The results of measurements of the tongue, its perimeter, length, and area in normal fetuses and in fetuses with chromosomal aberrations are discussed.

[The prediction of the condition of newborns on the basis of antepartum CTG monitoring and antepartum doppler flow velocity in umbilical arteries in women delivered by caesarean section].

Unlabelled: The aim of the study was the estimation of the condition of newborns delivered by caesarean section depending on antepartum umbilical Doppler flow velocity and CTG monitoring.

Material And Methods: In 213 pregnant women delivered by caesarean section (from preventive and urgent indications before beginning the labor) fetal monitoring included antepartum CTG and Doppler flow velocity up to 7 days before delivery. The CTG recordings before labour were interpreted using a Fischer's method.

[Concentration of procalcitonin in maternal blood, amniotic fluid and in umbilical cord blood as an indicator of neonatal infection].

Unlabelled: THE AIM of this study was to evaluate the usefulness of determining the concentration of procalcitonin (PCT) in the blood of pregnant women, in amniotic fluid and in umbilical blood as a predictor of intrauterine or infant infection.

Material And Methods: the study was conducted on the following material: pregnant women s blood, amniotic fluid and umbilical blood taken during delivery from 60 women and 60 infants. In this group there were 30 vaginal deliveries and 30 deliveries by caesarean section.

[Concentration of the soluble molecule ICAM-1 (sICAM-1) in the amniotic fluid as the marker of the intrauterine infection at pregnant women and at newborns].

Unlabelled: THE AIM of this study was to evaluate the usefulness of determining concentrations of sICAM-1 in amniotic fluid as an indicator of intrauterine infection in pregnant women and infants.

Material And Methods: the study was conducted on a group of 60 pregnant women by taking samples of amniotic fluid during delivery. Thirty of the women in the group had normal delivery and 30 had Caesarean section.

[Caesarean section in preterm labour].

The aim of this study was to estimate complications of pregnancy, indications to caesarean section, complications after caesarean operation and perinatal mortality of newborns who were delivered before the 37th week of gestation by caesarean section. The retrospective analysis of the total of 2693 deliveries (years 1991-2000) by caesarean section in the Department of Pregnancy and Labour Pathology in Pomeranian Academy of Medicine has been carried out. 590 women whose delivered before the 37th week of pregnancy have been chosen for subsequent examination.

[Pregnancy, labor and puerperium in patients with HELLP syndrome].

Objective: The aim of this study was to evaluate retrospectively 10 women with the syndrome of hemolysis, elevated liver enzymes, low platelets (HELLP)--age of patients, quality of antepartum medical care, clinical, biochemical parameters, treatment, course and duration of pregnancies, way of delivery, and puerperium.

Material And Methods: Women in the study group were divided in order of platelets (PLT) levels: 4 patients with PLT levels lower than 50 G/l and 6 patients with PLT levels higher than 50 G/l. The mean duration of pregnancies in both groups was similar.