Rubinstein-Taybi Syndrome in a 19-years old boy.

Introduction: Rubinstein-Taybi syndrome is a rare genetic multisystem disorder comprising motor organ dysfunction, craniofacial dysmorphism and psychomotor retardation, frequently with the abnormalities of the thyroid gland.

Objective: Presentation of a case of a 19-year-old patient with Rubinstein-Taybi syndrome in whom serum TSH, fT3 and fT4 levels were assessed.

Case: Craniofacial abnormalities including: microcephaly, underdeveloped maxilla, micrognathia, high arched palate, malocclusion, down-slanting palpebral fissures, thick eyelashes and full eyebrows.

The quantitative evaluation of the impact of viable medial meniscus graft type on the biochemical and biomechanical properties of the rabbit tibial cartilage.

Background: Knowledge of the impact of viable medial meniscus allograft and autograft transplantation on biochemical and mechanical properties of cartilage is needed to understand the development of joint osteoarthritis. The purpose of this study was to evaluate this relationship 6 months after viable medial meniscal autograft and allograft transplantation.

Methods: Twenty rabbits were chosen for the study.

Is resection of the tendon edge necessary to enhance the healing process? An evaluation of the expression of collagen type I, IL-1β, IFN-γ, IL-4, and IL-13 in the distal 1 cm of a torn supraspinatus tendon: part II.

Background: Type I collagen proin pro-in expression in a damaged supraspinatus tendon is thought to be dependent on the distance from the edge of the tear and the local expression of pro-inflammatory, anti-proliferative, and pro-proliferative cytokines. The study evaluates the expression of type I collagen, pro-inflammatory interleukin (IL) 1β, anti-proliferative interferon-γ (IFN-γ), and pro-proliferative IL-4 and IL-13 cytokines along a 1-cm section taken from the edge of a torn supraspinatus tendon. Three sections were taken: 3 mm distal to the tear, 3 mm proximal to the tear, and the 4-mm middle section between them.

Is resection of the tendon edge necessary to enhance the healing process? An evaluation of the homeostasis of apoptotic and inflammatory processes in the distal 1 cm of a torn supraspinatus tendon: part I.

Background: We hypothesize that the expression of proapoptotic and antiapoptotic molecules and cytokines is dependent on the distance from the torn supraspinatus tendon edge and this expression may influence its potential for healing. The aim of this work is to evaluate the expression of proapoptotic Bax molecule and caspases 3, 8, and 9; antiapoptotic Bcl-2 molecule; and proinflammatory tumor necrosis factor (TNF) α and anti-inflammatory interleukin 10 (IL-10) in 3 sections taken from a 1-cm section of the edge of a torn supraspinatus tendon: 3 mm distal and 3 mm proximal, as well as the remaining 4-mm middle section between them.

Methods: Nine patients, with a mean age of 58 years, were included in the study.

Assessment of apoptosis, MMP-1, MMP-3, TIMP-2 expression and mechanical and biochemical properties of fresh rabbit's medial meniscus stored two weeks under tissue culture conditions.

Introduction: The purpose of this study was to assess apoptosis, the expression of MMP-1, MMP-3 and TIMP-2, as well as the mechanical and biochemical properties of fresh rabbit medial meniscus after 2 weeks stored under tissue culture conditions.

Material And Methods: The study material included 26 rabbit's medial menisci. Fourteen menisci were stored for 2 weeks under tissue culture conditions.

Evaluation of effectiveness of osteoporosis treatment in patient with pachydermoperiostosis according to densitometric findings. Case study.

This study presents the outcome of osteoporosis treatment in a 29-year-old male patient with full-blown Touraine-Solente-Gole syndrome. His first DXA densitometry of the proximal femur demonstrated severe osteoporosis (BMD 0.628 g/cm(2); T-score -3.

Assessment of apoptosis and MMP-1, MMP-3 and TIMP-2 expression in tibial hyaline cartilage after viable medial meniscus transplantation in the rabbit.

Introduction: The porpuse of this animal study was to assess chondrocyte apoptosis and MMP-1, MMP-3 and TIMP-2 expression in rabbit tibial cartilage 6 months after viable medial meniscal autografts and allografts.

Material And Methods: Twenty white male New Zealand rabbits were chosen for the study. The medial meniscus was excised from 14 animals and stored under tissue culture conditions for 2 weeks, following which t of them were implantated as autografts and 7 as allografts.

Evidence for apoptosis, MMP-1, MMP-3 and TIMP-2 expression and their effect on the mechanical and biochemical properties of fresh viable knee medial meniscal allografts and autografts in the rabbit.

Introduction: The study sought evidence for apoptosis, the expression of MMP-1, MMP-3 and TIMP-2 and their effect on the mechanical and biochemical properties of rabbit fresh knee medial meniscal grafts in a 6-month follow-up.

Material And Methods: Forty white male New Zealand rabbits were chosen for the study. The medial meniscus was excised from 28 animals and stored under tissue culture conditions for 2 weeks, following which 14 of them were implanted as autografts and 14 as allografts.

[Double recurrent humerus osteochondroma].

This paper presents rare case of the double recurrent humerus osteochondroma in 18 years old man. Tumour was removed twice, in the age 5 and 10 years. In 18 years after tiny injury odoema and pain associated double, recurrent exostosis.

[Long-term results of using Pyrost in orthopedic operations--our own observations].

Based on clinical material of 21 patients age from 9 to 67 years (average 32.8 years) at whom bone defects were supplemented by Pyrost our own observations were presented. Only Pyrost was used in 10 cases, in 9 cases it was used together with homogenous bone grafts and in 2 with autogenous bone grafts.

[Effect of femoral shaft fracture for growth of the lower extremity in children].

On the material of 15 children aged from 1.5 to 15 years (mean 6.6), who were treated conservatively the influence of fracture of the femoral shaft for growth of the lower extremity was assessed.

[Operative treatment of Haglund's deformity].

The paper presents results of the operative treatment of 22 heel in 18 patients mostly young women from 13 to 31 years old (average 20.6) with Haglund's exostosis. Operative technique consisted in partial resection of the heel with removal of the Achilles bursa.