Arthroscopic Treatment of Osteochondral Lesions of the Talus in a Pediatric Population: A Minimum 2-Year Follow-up.

Background: Treatment of osteochondral lesions of the talus (OLTs) in children presents a difficult clinical challenge, with few large series reported.

Purpose: To evaluate functional and radiographic outcomes for children and adolescents undergoing arthroscopic treatment of symptomatic OLT with a minimum follow-up of 2 years.

Study Design: Case series; Level of evidence, 4.

Femoroacetabular impingement: current concepts in diagnosis and treatment.

As a result of reading this article, physicians should be able to: 1. Identify the etiology of femoroacetabular impingement. 2.

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

Runx transcription factors comprise a family of proteins that are essential for organogenesis. A unique nuclear matrix-targeting signal in the C terminus directs these factors to their appropriate subnuclear domains. At these sites, they interact with coregulatory proteins and target genes.

Sensory innervation of the ovotestis in the snail Helix aspersa.

Because oviposition in the land snail Helix aspersa is a metabolically expensive process coupled to a high fixed cost, one expects oviposition to occur only when the clutch size surpasses a minimum value at which the reproductive benefit exceeds the cost. We propose that neural innervation of the gonad allows H. aspersa to monitor oocyte production and ensure an adequate supply of gametes prior to ovulation.