Publications by authors named "Tomas OEstergaard Jensen"
Are C-reactive protein and procalcitonin safe and useful for antimicrobial stewardship purposes in patients with COVID-19? A scoping review.
Antimicrob Steward Healthc Epidemiol
September 2024
Article Synopsis
- This study aimed to evaluate how well C-reactive protein (CRP) and procalcitonin (PCT) can diagnose bacterial co-infections in COVID-19 patients and whether integrating them into antimicrobial stewardship programs is effective, particularly in ICU versus non-ICU settings.
- The study reviewed existing literature and included 59 studies, focusing on PCT’s predictive capabilities, antimicrobial stewardship goals, and contributions from low- and middle-income countries (LMICs).
- Findings indicated that in non-ICU COVID-19 patients from high-income countries, a PCT level below 0.25 mg/L could help rule out bacterial infections, but suggested that PCT should be assessed alongside other clinical indicators, and highlighted the
Objectives: This study aimed to compare antibody trajectories among individuals with SARS-CoV-2 hybrid and vaccine-induced immunity.
Methods: Danish adults receiving three doses of BTN162b2 or mRNA-1237 were included prior to first vaccination (Day 0). SARS-CoV-2 anti-spike IgG levels were assessed before each vaccine dose, at Day 90, Day 180, 28 days after 3rd vaccination (Day 251), Day 365, and prior to 4th vaccination (Day 535).
Objective: To assess the degree of hypoxia and subjective dyspnea elicited by a 6-minute walking test (6MWT) in COVID-19 patients prior to discharge.
Methods: A 6MWT was performed in 26 discharge-ready COVID-19 patients without chronic pulmonary disease or cardiac failure. Heart rate, oxyhemoglobin saturation (SpO), respiratory rate, and subjective dyspnea measured on the Borg CR-10 scale were measured before and immediately after the 6MWT, with continuous monitoring of SpO and heart rate during the 6MWT.