Publications by authors named "Tomas Lucca Bothe"
Pulse wave velocity (PWV) has been established as a promising biomarker in cardiovascular diagnostics, providing deep insights into vascular health and cardiovascular risk. Defined as the velocity at which the mechanical wave propagates along the arterial wall, PWV represents a useful surrogate marker for arterial vessel stiffness. PWV has garnered clinical attention, particularly in monitoring patients suffering from vascular diseases such as hypertension and diabetes mellitus.
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- Orthostatic dysregulation can happen when people return to normal gravity after being in microgravity, which is common in space travel; external peripheral skin cooling (PSC) has been proposed as a potential solution to this issue.
- A study called "Coolspin" was conducted with 18 healthy male volunteers, testing PSC while subjected to increased gravitational forces (up to +4g) in a centrifuge, measuring various cardiovascular parameters.
- The results showed that PSC did not significantly improve cardiovascular stability or hemodynamic activity during +Gz, suggesting that the cooling method used may not have been adequate or the subjects' responses to cooling were low, indicating a need for further research.
Objective: The objective of this study is to evaluate the accuracy of the oscillometric upper-arm device ABPMpro (SOMNOmedics) for ambulatory blood pressure measurement in the general population according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Universal Standard (ISO 81060-2:2018) at rest and during dynamic exercise.
Methods: Subjects were recruited to fulfill the age, sex, blood pressure (BP) and cuff distribution criteria of the AAMI/ESH/ISO standard using the same arm sequential BP measurement method. Three appropriate cuff sizes (18-24, 24-34 and 34-46 cm) of the tested device were used for the arm-varying circumferences.