Publications by authors named "Tomas Gruszka"
Background: Severe or critical congenital heart defects (CHDs) constitute one third of the heart defect cases detected only after birth. These prenatally unrecognised defects usually manifest as cyanotic or acyanotic lesions and are diagnosed postnatally at various times. The aim of the study was to identify their clinical symptoms and determine individual risk periods for CHD manifestation.
View Article and Find Full Text PDFArea of the right atrium of the fetal heart and its significance in fetuses with tricuspid regurgitation.
J Matern Fetal Neonatal Med
December 2022
Objectives: The first aim was to develop a nomogram for the area of the right atrium (ARA) of the fetal heart in uncomplicated singleton pregnancies. The second aim was to assess diagnostic indices of ARA to distinguish between tricuspid regurgitation (TR) with and without concomitant congenital heart defect (CDH).
Methods: The study was conducted between 2014 and 2019.
Congenital fetal heart defect - an agreement between fetal echocardiography and autopsy findings.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
March 2020
Article Synopsis
- The study examined how often pregnancies are terminated due to congenital heart defects (CHD) and compared fetal echocardiography (FECHO) with autopsy findings.
- Between 2008 and 2017, out of 116,698 live births, 293 CHDs were identified, and 49% of families chose to terminate the pregnancy, with autopsy confirming CHDs in 99% of those cases.
- FECHO demonstrated a high agreement with autopsy findings (85%) but missed some minor defects; it is effective for detecting CHD, yet not exhaustive in identifying all cardiac issues.
Article Synopsis
- The study aimed to investigate how common fetal heart tumors are at a single referral center over 15 years, focusing specifically on rhabdomyomas linked to tuberous sclerosis complex (TSC).
- It involved examining 39,018 fetuses from 2003 to 2017, with echocardiograms performed in the second trimester and follow-ups conducted by a pediatric cardiologist.
- The findings revealed nine cases of heart tumors, all rhabdomyomas, with a confirmed genetic link to TSC in eight of these cases, indicating potential neurological issues for affected newborns.
This study aimed to evaluate the prenatal rate of congenital heart defects (CHDs) and the frequency of termination of pregnancy (TOP) due to a CHD, depending on the severity of the defect and concomitant diseases of the fetus. The data were assessed retrospectively between 2002 and 2017. Ultrasound examination was performed mostly in the second trimester.
View Article and Find Full Text PDFAssociations between congenital heart defects and genetic and morphological anomalies. The importance of prenatal screening.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
February 2019
Article Synopsis
- The study investigates congenital heart defects (CHDs) and their connections to other health issues outside the heart, along with the importance of prenatal screening.
- From 1999 to 2017, data revealed that 3.7 cases of significant CHDs were detected per 1,000 fetuses, with over half diagnosed before birth.
- Results showed that most CHDs were isolated defects, but about one-third were associated with genetic or extra-cardiac anomalies, highlighting the critical role of prenatal diagnostics in identifying these conditions early.
Congenital heart defects according to the types of the risk factors - a single center experience.
J Matern Fetal Neonatal Med
November 2019
The main aim of this study was to compare the prevalence of congenital heart defects (CHDs) between pregnant women with and those without the risk factors. The secondary aim was to determine the influence of the specific risk factors, divided into subgroups, on the development of the CHD. The presented results were obtained over the course of a 15-year study between years 2002 and 2016.
View Article and Find Full Text PDF