Publications by authors named "Tomas Florian"
Effects of prenylated isoflavones osajin and pomiferin in premedication on heart ischemia-reperfusion.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
July 2006
Article Synopsis
- The study evaluates the cardioprotective effects of osajin and pomiferin, two compounds isolated from the fruit of Maclura pomifera, using rat hearts as a model for testing antioxidant therapy against ischemia-reperfusion injury.
- The research involved four groups of Wistar rats, where two groups received the isoflavones, while the other two served as a placebo and control group, with various biochemical and functional heart parameters measured after treatment.
- Results indicated that both osajin and pomiferin improved heart function and decreased oxidative stress, suggesting their potential as protective agents against heart damage caused by ischemia-reperfusion events.
Influence of antioxidant effect of stobadine derivative in condition of kidney ischemia-reperfusion in a pre-clinical experiment (effect in prophylaxis).
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
December 2005
The goal of the study was to monitor the antioxidative effect of stobadine derivative in the conditions of ischemia-reperfusion of laboratory rat kidney tissue. The animals were divided by random selection into 5 groups (n = 10). The treated groups were given stobadine derivate in peroral doses of 5, 10 and 20 mg/kg in 0.
View Article and Find Full Text PDFInfluence of antioxidant effect of stobadine derivative in condition of kidney ischemia-reperfusion in a pre-clinical experiment (effect in therapy).
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
December 2005
The goal of the study was to monitor the antioxidative effect of stobadine derivative under conditions of ischemia-reperfusion of laboratory rat kidney tissue. 40 animals were subjected to kidney tissue ischemia (60 min) followed by reperfusion (10 min). After that, the animals were divided by random selection into 4 groups (n = 10).
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