Extracellular Vesicles Secreted by Have COX and Proteolytic Activity and Induce Hemolysis.

Several species of genus are potential pathogens and etiological agents of several diseases. The pathogenic mechanisms carried out by these amoebae in different target tissues have been documented, evidencing the relevant role of contact-dependent mechanisms. With the purpose of describing the pathogenic processes carried out by these protozoans more precisely, we considered it important to determine the emission of extracellular vesicles (EVs) as part of the contact-independent pathogenicity mechanisms of , a highly pathogenic strain.

trophozoites that survive multipurpose solutions are able to adhere to cosmetic contact lenses, increasing the risk of infection.

Amoebae of the genus are etiological agents of amoebic keratitis, for which up to now there is no treatment of choice and one of its main risk factors is the use of contact lenses, including cosmetic contact lenses. Recently there has been an increase in amoebic keratitis cases due to the use of cosmetic contact lenses. Therefore, having a solution for the care of lenses with an efficient disinfectant effect that prevents the adhesion of trophozoites to lenses becomes essential.

Morphological Description of the Early Events during the Invasion of Trophozoites in a Murine Model of Skin Irradiated under UV-B Light.

Skin infections have been associated with , nevertheless the events during skin invasion and UV-B light effects on it are unknown. The early morphological events of skin invasion are shown in SKH-1 mice that were chronically UV-B light irradiated. Mice that developed skin lesions (group 1) were topical and intradermally inoculated with trophozoites and sacrificed 48 h or 18 days later.