A well-defined chicken osteoblast culture system(18) has been used to examine fibronectin (FN) mRNA levels, synthesis, and accumulation during in vitro differentiation and matrix mineralization. Immunofluorescent staining of cells after 6 or 18 days in culture revealed that FN was initially associated with the cell surface and in partial coalignment with cytoskeletal elements while at the latter time most FN was associated with the extracellular matrix as a ubiquitous fibrillar network. Western blot analysis of total cell-associated proteins also detected FN at all culture times.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
July 1995
The influence of reducing external Na+ concentration ([Na+]ex) upon vascular smooth muscle contractility was investigated using the rat isolated aorta. NaCl from the physiological saline solution (PSS) was replaced with either choline-Cl, sucrose, or LiCl to give the following [Na+]ex (mM): 115, 85, 55, and 25 (115NaPSS to 25NaPSS). Small reductions in [Na+]ex (115NaPSS) induced a biphasic contraction, comparable in amplitude with the control one induced by phenylephrine 10(-6) M.
View Article and Find Full Text PDFPurpose: To investigate whether serum levels of lipid peroxides measured as thiobarbituric-acid-reactive substances (TBARS) differ in type I and type II diabetic patients, whether serum levels correlate with late sequelae of diabetes, and whether serum levels of free vitamin E correlate with levels of lipid peroxidation by-products.
Patients And Methods: The relationship among lipids, glycosylated hemoglobin A1c (HbA1c), lipid peroxides measured as TBARS, and free vitamin E was determined in 158 patients. Fifteen of the 77 patients with type I diabetes and 39 of the 81 patients with type II diabetes had clinically apparent peripheral vascular disease or coronary artery disease, or both.
1. A pharmacological characterization of tyrosine kinase inhibitors (TKI) belonging to two distinct groups (competitors at the ATP-binding site and the substrate-binding site, respectively) was performed, based on their effects on the contractility of rat mesenteric arteries. 2.
View Article and Find Full Text PDFAnn Gastroenterol Hepatol (Paris)
August 1995
Rom J Morphol Embryol
August 1996
Congenital ichthyosiform erythroderma (C.I.E.
View Article and Find Full Text PDFHuman umbilical vein endothelial cells were incubated with Bretschneider and St. Thomas II cardioplegic solution followed by a stimulation with cumene hydroperoxide (CHPO), which was used as an oxygen radicals generating agent. A statistically significant decrease of intracellular high energy phosphates (adenosine-5-trisphosphate: ATP; creatine phosphate: CP) compared to controls was observed in response to Bretschneider cardioplegia and CHPO.
View Article and Find Full Text PDFZ Orthop Ihre Grenzgeb
March 1994
85 patients with 96 cementless pressfit hip implants were followed over a period of at least 5 years postoperatively. Average Harris score was 87.5 points.
View Article and Find Full Text PDFRom J Morphol Embryol
March 1995
Thirty-six cases of bronchopulmonary carcinoid tumor were reviewed in order to identify the clinicomorphologic criteria whereby typical and atypical carcinoids can be classified as two distinct entities. This study indicates that bronchial typical carcinoids are tumors with very low malignancy, more often centrally located and occurring in relatively young patients. The prognosis is good, with a five year-survival rate of about 73%, although regional nodal metastases may occasionally develop.
View Article and Find Full Text PDFRom J Morphol Embryol
March 1995
Tissue samples from six patients suffering from lichen planus (L. P.), with oral and genital localization were examined by light and transmission electron microscopy, in order to better define the structural and ultrastructural changes that are correlated with L.
View Article and Find Full Text PDFEighty-five patients with 96 cementless press-fit hip implants were followed over a period of at least 5 years postoperatively. The average Harris score was 87.5 points.
View Article and Find Full Text PDFBacteriol Virusol Parazitol Epidemiol
February 1993
Int J Psychol
January 1989
Cognitive processes underlying Stroop interference tasks of two Japanese orthographies, hiragana (a phonetic orthography) and kanji (a logographic orthography) were studied from the developmental point of view. Four age groups (first, second, third graders, and university students) were employed as subjects. Significant interference was yielded both in the hiragana and in the kanji version.
View Article and Find Full Text PDFNeurol Psychiatr (Bucur)
November 1985
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol
April 1982
Rev Pediatr Obstet Ginecol Pediatr
January 1981