Utilizing MRI, [F]FDG-PET and [Zr]Zr-DFO-28H1 FAP-PET tracer to assess inflammation and fibrogenesis in a reproducible lung injury rat model: a multimodal imaging study.

Objective: Accurate imaging biomarkers that indicate disease progression at an early stage are highly important to enable timely mitigation of symptoms in progressive lung disease. In this context, reproducible experimental models and readouts are key. Here, we aim to show reproducibility of a lung injury rat model by inducing disease and assessing disease progression by multi-modal non-invasive imaging techniques at two different research sites.

The influence of endorectal filling on rectal cancer staging with MRI.

Objective: To assess the influence of endorectal filling (EF) on rectal cancer staging.

Methods: 47 patients who underwent a staging MRI of rectal cancer in the period from 2011 to 2014 were included. The MRI protocol included T weighted fast spin echo sequences without and with EF at 3 T (EF-MRI).