Reproducibility of electrical sensory testing in lower urinary tract at weekly intervals in healthy volunteers and women with non-neurogenic detrusor overactivity.

Objective: To evaluate the reproducibility of a standardized technique of current perception threshold measurements with square wave and sine wave current, with monopolar and bipolar electrodes in a cohort of patients with overactive bladder (OAB) and healthy volunteers.

Methods: We enrolled 6 female nulliparous healthy volunteers and 11 female patients with OAB. Current perception threshold measurements of the bladder were performed using several techniques.

Reproducibility of urodynamic filling sensation at weekly interval in healthy volunteers and in women with detrusor overactivity.

Aims: To evaluate the reproducibility of bladder sensation during standardized filling cystometry in female volunteers and overactive bladder (OAB) patients, repeated with weekly interval.

Methods: We recruited 13 female nulliparous volunteers (age 21-47) and 17 female patients with OAB between (age 18-72). They participated in three investigation periods, each separated by 7 days to assess reproducibility of sensation related to standardized cystometry.

How do different tests evaluate sensation in the lower urinary tract?

Objective: Different tests can be used to evaluate lower urinary tract (LUT) sensation. The purpose of this study is to compare sensory tests in patients with voiding disorders.

Material And Methods: Seventy patients with various functional disorders of the LUT were admitted for a cystometry and an electrical perception threshold test of the bladder (bEPT) and distal urethra (uEPT).

The effect of intravesical oxybutynin on the ice water test and on electrical perception thresholds in patients with neurogenic detrusor overactivity.

Aims: The C-fiber-mediated bladder-cooling reflex and the determination of the current perception thresholds (CPTs) permit to investigate afferent LUT pathways. They have both been proposed to detect and differentiate neurologic bladder dysfunction. This study evaluates, prospectively, the effect of oxybutynin, an antimuscarinic with direct antispasmodic effect on smooth muscle, on repeated ice water test (IWT) and CPTs in patients with a known incomplete neurogenic bladder.

Does sensory bladder function during cystometry differ from that in daily life? A study in incontinent women.

Aims: Daily life bladder sensation can be evaluated by sensation related bladder diary (SR-BD). Sensation can also be studied during cystometric bladder filling (CBF). We compared results of both methods in incontinent women.

Repeated ice water tests and electrical perception threshold determination to detect a neurologic cause of detrusor overactivity.

Objectives: To explore the added value of a repeated ice water test (IWT) and electrical perception threshold (EPT) measurement in the search for a neurologic cause of idiopathic detrusor overactivity (DOA).

Methods: The IWT, if originally negative, was repeated up to three times, and EPT measurements were done in 63 patients with neurologic DOA, 117 patients with idiopathic DOA without outflow obstruction, and 30 women with stress urinary incontinence without DOA.

Results: Although the IWT was positive in 46% of the neurologic patients if used once, this percentage became 86% when the IWT was repeated.

Can a faked cystometry deceive patients in their perception of filling sensations? A study on the reliability of spontaneously reported cystometric filling sensations in patients with non-neurogenic lower urinary tract dysfunction.

Aims: To evaluate the reliability of spontaneously reported bladder sensations during real and faked cystometry in patients with non-neurogenic lower urinary tract dysfunction.

Methods: Fifty-nine patients with non-neurogenic lower urinary tract dysfunction were submitted to a real and faked filling cystometry and were asked to describe all bladder-related sensations they experienced during the investigations. All patients were told that the bladder had to be filled twice, but during the faked cystometry, no water was infused in the bladder.

Detrusor overactivity. Does it represent a difference if patients feel the involuntary contractions?

Purpose: We evaluated the differences between patients with overactive bladder (OAB) who felt involuntary detrusor contractions during cystometry (detrusor overactivity [DO]) and those who did not feel them.

Materials And Methods: We prospectively studied 45 patients with symptoms of nonneurogenic, nonobstructed overactive bladder and with DO on cystometry. All patients underwent videourodynamics, the ice water test and electrical perception threshold determination.