Publications by authors named "Tom J. Stoof"

Background And Aim: Vulval Crohn's disease (VCD) is a rare extraintestinal cutaneous manifestation of Crohn's disease. No consensus on the diagnostic workup and therapeutic management of this condition has been provided in the current literature.

Patients And Methods: Retrospective, multicentre descriptive case series of female patients diagnosed and treated with VCD.

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A 58-year-old man presented with a necrotizing ulcus on his back due to a complicated fluoroscopy-guided intervention procedure a few months before with a high total radiation dose.

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Human papillomavirus (HPV) infections and HPV-associated penile lesions are frequently found in male sexual partners of women with cervical intraepithelial neoplasia (CIN). To determine the significance of these findings, we studied the prevalence of HPV and HPV associated penile lesions in a male hospital population with non-STD complaints. Penoscopy was performed after application of acetic acid to identify flat lesions, papular lesions, condylomata acuminata and pearly penile papules (PPPs).

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Article Synopsis
  • Allergic contact dermatitis (ACD) is a T-cell-mediated condition that leads to skin inflammation and involves specific chemokines that attract T cells to the skin.
  • While we understand some chemokines that initiate ACD, the reasons behind T-cell retention in the skin after inflammation has resolved are still unclear.
  • This study highlights that the chemokine CCL27 remains elevated in the skin even weeks after the inflammation has subsided, correlating with the presence of certain T cells, suggesting a mechanism for skin memory and quicker reactions to allergens in the future.
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Extraintestinal complications of inflammatory bowel disease (IBD) are often secondary to the underlying disease. Therefore, the first priority is to get active IBD into remission with medications, since surgery for IBD is not indicated for the treatment of extraintestinal complications. Symptoms of extraintestinal complications usually can be treated with simple agents; the treatment of patients with refractory symptoms and the use of more complex drug regimens should be done in cooperation with specialists on affected organ systems.

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