Importance: Systemic lupus erythematosus (SLE) predisposes individuals to early cardiovascular (CV) events. While hydroxychloroquine is thought to mitigate CV risk factors, its protective role against CV events, particularly arterial ones, remains to be confirmed.
Objective: To evaluate the association between hydroxychloroquine and the risk of myocardial infarction (MI), stroke, and other thromboembolic events (OTEs) in patients with SLE.
Importance: Scientific literature is sparse about the association of vaccination with the onset of multiple sclerosis (MS) flare-ups. Immunization by vaccines of the entire population is crucially important for public health.
Objective: To evaluate the risk of hospitalization for severe MS flare-ups after vaccination in patients with MS.
Motivation: Public health authorities monitor cases of health-related problems over time using surveillance algorithms that detect unusually high increases in the number of cases, namely aberrations. Statistical aberrations signal outbreaks when further investigation reveals epidemiological significance. The increasing availability and diversity of epidemiological data and the most recent epidemic threats call for more accurate surveillance algorithms that not just detect aberration times but also detect locations.
View Article and Find Full Text PDFObjectives: To quantify the burden of COVID-19-related sick leave during the first pandemic wave in France, accounting for sick leaves due to symptomatic COVID-19 ('symptomatic sick leaves') and those due to close contact with COVID-19 cases ('contact sick leaves').
Methods: We combined data from a national demographic database, an occupational health survey, a social behaviour survey and a dynamic SARS-CoV-2 transmission model. Sick leave incidence from 1 March 2020 to 31 May 2020 was estimated by summing daily probabilities of symptomatic and contact sick leaves, stratified by age and administrative region.
The microorganisms found on fresh, raw meat cuts at a slaughterhouse can influence the meat's safety and spoilage patterns along further stages of processing. However, little is known about the general microbial ecology of the production environment of slaughterhouses. We used 16s rRNA sequencing and diversity analysis to characterize the microbiota heterogeneity on conveyor belt surfaces in the cutting room of a swine slaughterhouse from different production lines (each associated with a particular piece/cut of meat).
View Article and Find Full Text PDFBackground: Workplace absenteeism increases significantly during influenza epidemics. Sick leave records may facilitate more timely detection of influenza outbreaks, as trends in increased sick leave may precede alerts issued by sentinel surveillance systems by days or weeks. Sick leave data have not been comprehensively evaluated in comparison to traditional surveillance methods.
View Article and Find Full Text PDFThe identification of sick leave determinants could positively influence decision making to improve worker quality of life and to reduce consequently costs for society. Sick leave is a research topic of interest in economics, psychology, health and social behaviour. The question of choosing an appropriate statistical tool to analyse sick leave data can be challenging.
View Article and Find Full Text PDFObjective: We hierarchized a range of individual and occupational factors impacting the occurrence of very short (1-3 days), short (4 days to 1 month), or long-term (more than a month) sick leave spells.
Methods: Data were collected from a repeated cross-sectional survey conducted in the French private sector over the period 2011 to 2017. Fifty one sick leave determinants were ranked using a conditional random forest approach.
Background: The parasitic nematode Haemonchus contortus shows highly variable life history traits. This highlights the need to have an average estimate and a quantification of the variation around it to calibrate epidemiological models.
Methods: This paper aimed to quantify the main life history traits of H.