Synopsis of recent research by authors named "Tom Alsaigh"
- Tom Alsaigh's recent research primarily focuses on atherosclerosis and its inflammatory characteristics, exploring innovative therapeutic approaches such as pro-efferocytic nanotherapies and advanced imaging techniques like near-infrared photoacoustic imaging to identify vulnerable plaques.
- His studies emphasize the impact of combined treatments, particularly the synergistic effects of statins and angiotensin-converting enzyme inhibitors (ACE-Is) in improving outcomes for patients undergoing carotid revascularization procedures.
- Alsaigh employs cutting-edge methodologies, including single-cell RNA sequencing and genome-wide analysis, to decode the complex cellular dynamics and transcriptional profiles in atherosclerotic lesions, aiming to elucidate the molecular mechanisms behind vascular smooth muscle cell transitions during atherogenesis.