Publications by authors named "Tolulope O Awosika"
Tissue Eng Part A
March 2020
Article Synopsis
- The formation of viable tissue surrogates relies heavily on developing a vascular network through the coculture of endothelial cells (ECs) and mesenchymal stem cells (MSCs), which play crucial roles in blood vessel formation.
- There is conflicting evidence about whether MSCs promote or inhibit the formation of blood vessels, as they can have both proangiogenic and antiangiogenic effects depending on the conditions.
- A study using bioprinting techniques found that MSCs initially inhibit angiogenic factor expression by ECs, but later contribute positively to blood vessel formation, with different signaling mechanisms at play in direct versus indirect cocultures.
