Publications by authors named "Tolstrup J"

Background: The role of carbohydrates in diabetes risk is of particular interest due to conflicting results. This study aims to examine the prospective association between types of dietary carbohydrates (fiber, starch, total sugar, glucose, fructose, lactose, maltose, and added sugar) and the risk of diabetes. Further, this study examines the cross-sectional associations between these nutrients and cardiometabolic risk factors.

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Background: Individuals with problematic alcohol use often face anxiety and depressive symptoms, which can hinder treatment engagement, compliance, and effectiveness. Psychosocial therapy through video conference (e-alcohol therapy) may reduce these barriers. We explored whether 1) anxiety or/and depressive symptoms modify the effect of proactive e-alcohol therapy on treatment initiation, compliance, and alcohol intake, 2) proactive e-alcohol therapy impacts anxiety or/and depressive symptoms compared to standard care.

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Introduction: Per- and polyfluoroalkyl substances (PFASs) have immunotoxic effects in children while studies in adults, including recent studies on the SARS-CoV-2 vaccine response have been less consistent. In a cohort of 50-69-year-olds repeatedly vaccinated against COVID-19 in Denmark from early 2021, we aimed to assess the association between serum-PFAS concentrations and SARS-CoV-2 antibody responses.

Methods: We assessed serum-PFAS concentrations among 371 middle-aged adults from the National Cohort Study of Effectiveness and Safety of SARS-CoV-2 vaccines (ENFORCE) who had received their first vaccination against COVID-19.

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Objective: To assess inequalities in all cause and cause specific mortality in young people and if there are differences across gender and age groups.

Design: Nationwide cohort study of socioeconomic predictors.

Setting: Denmark, 1 January 2010 to 31 December 2022.

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Background: Using data from a nationwide survey among high school students in Denmark, the aim of the current study is to measure the prevalence of online bullying and online sexual harassment and assess gender and age differences in exposure.

Methods: We used data from the Danish National Youth Study 2019, which is a nationwide web survey among high school students, including general, commercial, preparatory and technical high schools. Data were collected from January to April 2019 through a self-administered questionnaire in the classroom.

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Aim: To study social disparity in acute pancreatitis (AP) and chronic pancreatitis (CP).We also aimed at exploring whether an interaction exists between alcohol intake and socioeconomic factors.

Methods: Prospective cohort study based on data from 271 696 men and women participating in the Danish National Health Surveys 2010, and 2013.

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Background: Few people with problematic alcohol use reach treatment and dropout is frequent. Therapy for problematic alcohol use delivered via video conference (e-alcohol therapy) might overcome treatment barriers. In this randomised study, we tested whether proactive e-alcohol therapy outperformed face-to-face alcohol therapy (standard care) regarding treatment initiation, compliance, and weekly alcohol intake at 3-month and 12-month follow-up.

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Article Synopsis
  • The study aimed to adapt an existing UK-based home cardiac rehabilitation program (REACH-HF) to fit the Danish health system, creating a new variant called 'DK:REACH-HF.'
  • Researchers employed various methods, including documentary analysis, qualitative interviews, and stakeholder consultations, and found strong support for the adapted intervention.
  • Key adaptations involved simplifying resources, customizing content for the Danish context, and creating both paper and digital versions of the intervention, with plans for a pilot study to evaluate its feasibility and effectiveness.
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Aim: The aim was to identify maternal and paternal socioeconomic and demographic characteristics for non-initiation and non-completion of the human papillomavirus (HPV) vaccination among Danish girls including time-trends.

Methods: This nationwide register-based cohort study included all girls residing in Denmark who were offered free-of-charge HPV vaccination as a part of the childhood vaccination program between 2009 and 2018 (birth cohorts 1996-2005). The study samples included 296,461 daughter-mother dyads and 291,025 daughter-father dyads.

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Introduction: Solitary fibrous tumor (SFT) is a rare soft tissue tumor found at any site of the body. The treatment of choice is surgical resection, though 10%-30% of patients experience recurrent disease. Multiple risk factors and risk stratification systems have been investigated to predict which patients are at risk of recurrence.

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In Denmark, the proportion of children completing the HPV vaccination program is lower than for other vaccines, and the relatively low uptake is believed to be influenced by a media debate on suspected side effects of HPV vaccination. Based on a systematic PubMed search, this review identified 14 Danish studies that compared symptoms or disease incidence among HPV-vaccinated individuals with the incidence in a control group. Most studies showed no association between HPV vaccination and subsequent illness.

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In February 2022, Russia invaded Ukraine. The Putin regime used extensive and aggressive propaganda to win public support for the war. But can this propaganda really convince ordinary people? Using the unique timing of a survey experiment fielded a year before the invasion, we provide the first experimental evidence of the effectiveness of this propaganda among Russian citizens.

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Article Synopsis
  • A study examined the link between alcohol consumption and hospital visits for injuries among 71,025 Danish students aged 15-24 over five years, highlighting the significant health risks posed by alcohol use in adolescents.
  • Around 90% of participants reported drinking, with males averaging 11 drinks per week and females 8, leading to 13% experiencing alcohol-related hospital contacts, primarily from acute intoxication.
  • The analysis revealed a strong dose-response relationship; the risk of hospitalization increased markedly with higher weekly alcohol intake, where drinking more than 27 drinks per week was associated with a 3.25 times greater risk compared to non-drinkers.
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Introduction: The epidemic increase in obesity is well documented and of intensive public health interest. Attention has almost entirely focused on a dichotomous measure of obesity such as how the prevalence of BMI ≥ 30 kg/m2 has changed over time. Less consideration has been given to how the general distribution of BMI has evolved.

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Background: Adolescent hazardous alcohol use is prevalent and has serious short- and long-term consequences. The trial 'Our Choice' examines efficacy, feasibility and acceptability of prevention interventions targeting school, parent, and student levels at Danish high schools. We hypothesize that students in a structural intervention (school and parent levels) reduce hazardous alcohol use and related health behaviors compared to students in an assessment only control group 12 months post baseline; and that adding group-based Motivational Interviewing (group MI) yields further improvements.

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Purpose: During the teenage years, many adolescents start drinking alcohol, and binge drinking is prevalent. We investigated the relationship between alcohol intake and academic performance.

Methods: We conducted a longitudinal cohort study by combining data from the Danish National Youth Study on 65,233 high school students aged 15-20 years, with information on dropout and grade point average.

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Background: National comprehensive smoke-free legislation has been found to decrease the incidence of several smoking-related diseases. In 2007, Denmark introduced a national smoking ban, which banned smoking indoor in workplaces and public places, although only partial restrictions were applied in certain settings. We examined the impact of the smoking ban on smoking-related diseases and whether this differed across socioeconomic groups.

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Background: Evidence shows that similar levels of alcohol consumption lead to greater harm in adults with low socioeconomic position (SEP) compared to high SEP. We investigated if SEP is associated with alcohol-related hospital contacts in adolescents, and whether differences in risk can be explained by differences in levels of alcohol consumption, drinking pattern, and substance use.

Methods: This is a prospective cohort study of 68,299 participants aged 15-19 years old from the Danish National Youth Cohort 2014.

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Aim: The aim of this study was to investigate changes in the prevalence of loneliness in Denmark from 2000 to 2021 by conducting age-period-cohort analysis.

Methods: Our study was based on a sample (=83,437; age: ⩾16 years) of the Danish Health and Morbidity Surveys conducted in Denmark in 2000, 2005, 2010, 2013, 2017 and 2021. We used logistic regression models by gender to estimate the age-period-cohort effects, with loneliness as the dependent variable and age, survey year and birth cohort as independent variables, mutually adjusted.

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71% of the Danish municipal alcohol treatment centres use NADA acupuncture. This status report based on recent reviews of the effect and risks of using auricular acupuncture in alcohol treatment shows that the available studies do not have sufficient strength and methodological quality to draw conclusions about effectiveness on craving, alcohol-related outcome measures or withdrawal symptoms. The results warrant a reassessment of the use of NADA in publicly funded alcohol treatment.

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Article Synopsis
  • Milk production during breastfeeding is influenced by hormones and can be affected by exposure to endocrine-disrupting chemicals, especially per- and polyfluoroalkyl substances (PFAS).
  • PFAS exposure may result in negative outcomes such as underdeveloped mammary glands in animals and shorter breastfeeding durations in humans, prompting a review of relevant studies.
  • A systematic search identified six studies that consistently linked higher PFAS exposure to reduced breastfeeding duration, particularly with specific PFAS compounds like PFOS, PFOA, and PFNA.
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