Investigation of the dose-dependency of citicoline effects on nerve regeneration and functional recovery in a rat model of sciatic nerve injury.

Aim: The aim of this study was to investigate the dose dependence of citicoline's previously-reported effects on recovery of peripheral nerve injury.

Material And Methods: Right sciatic nerves of sixty adult female Wistar Albino rats were incised and primary anastomosis was performed. Rats were then divided into four groups: Control group received 2 ml of saline intraperitoneally, while rats in C-300, C-600 and C-900 groups received 300 μmol/kg, 600 μmol/kg and 900 μmol/kg citicoline dissolved in 2 ml saline, respectively.

Comparative results of percutaneous cannulated screws, dynamic compression type plate and screw for the treatment of femoral neck fractures.

Background: The purpose of this study was to compare the period of union, functional outcomes and complications of patients with femoral neck fracture treated with percutaneous cannulated screws versus dynamic hip screw (DHS).

Methods: Sixty-six patients with femoral neck fracture were treated with percutaneous cannulated screws (n=33) or with DHS (n=33) between August 1999 and October 2003. Functional outcome was measured using Harris Hip Score, and period of union, amount of bleeding and complications were also recorded.

Enhancement of tendon-bone healing of anterior cruciate ligament grafts by blockage of matrix metalloproteinases.

Background: The use of soft-tissue grafts for anterior cruciate ligament reconstruction delays the healing process. This delay may be due to biochemical and/or biomechanical insults. We hypothesized that the blocking effect of alpha2-macroglobulin on synovial matrix metalloproteinase activity may enhance the healing of tendon graft in a bone tunnel.

[The "false sense of absence" of the lower extremity below the knee: is it a specific sign for anterior cruciate ligament ruptures?].

Objectives: Patients whose anterior cruciate ligament (ACL) was completely ruptured described a feeling as if they had lost their lower extremity below the knee and gave an account that they had not sensed that part of their extremity at the time of ACL rupture. Thinking that this description might denote a diagnostic sign, an investigation was made to verify this feeling in patients whose ACL rupture was confirmed by knee arthroscopy.

Methods: The described feeling was named as "false sense of absence.