CAECENET: An automatic system processing photometer and ceilometer data from different networks to provide columnar and vertically-resolved aerosol properties.

This work introduces CAECENET, a new system capable of automatically retrieving columnar and vertically-resolved aerosol properties running the GRASP (Generalized Retrieval of Atmosphere and Surface Properties) algorithm using sun-sky photometer (aerosol optical depth, AOD; and sky radiance measurements) and ceilometer (range corrected signal; RCS) data as input. This method, so called GRASPpac, is implemented in CAECENET, which assimilates sun-sky photometers data from CÆLIS database and ceilometer data from ICENET database (Iberian Ceilometer Network). CAECENET allows for continuous and near-real-time monitoring of both vertical and columnar aerosol properties.

Phase 2, Multicenter, Open-label, Nonrandomized Study of Neoadjuvant Chemotherapy Liposomal Irinotecan With 5-Fluorouracil, Leucovorin, and Oxaliplatin, Followed by Chemoradiotherapy in Patients With Rectal Cancer in a Watch-and-Wait Program.

Objective: To evaluate the efficacy of neoadjuvant chemotherapy combination with liposomal irinotecan, 5-fluorouracil, leucovorin, and oxaliplatin in patients with locally advanced rectal cancer.

Methods: This was a phase 2, nonrandomized, multicenter study in adults with stage II or III rectal cancer and an Eastern Cooperative Oncology Group performance status of 0 to 1. Total neoadjuvant therapy (TNT) consisted of neoadjuvant chemotherapy combination with liposomal irinotecan (60 mg/m2), oxaliplatin (60 mg/m2), leucovorin (400 mg/m2), and fluorouracil (2400 mg/m²), followed by chemoradiotherapy [ie, capecitabine (825 mg/m2) and radiotherapy according to the standard of care].

ORION software tool for the geometrical calibration of all-sky cameras.

This paper presents the software application ORION (All-sky camera geOmetry calibRation from star positIONs). This software has been developed with the aim of providing geometrical calibration to all-sky cameras, i.e.

MAB-MIG: registry of the spanish neurological society of erenumab for migraine prevention.

Background: Erenumab was approved in Europe for migraine prevention in patients with ≥ 4 monthly migraine days (MMDs). In Spain, Novartis started a personalized managed access program, which allowed free access to erenumab before official reimbursement. The Spanish Neurological Society started a prospective registry to evaluate real-world effectiveness and tolerability, and all Spanish headache experts were invited to participate.

Inhaled corticosteroids may have a protective effect against coronavirus infection.

Background: Spain has been severely affected by the COVID-19 epidemic, with 195,944 persons infected and 20,453 deaths at the time of writing. Older people with respiratory or cardiac conditions are most at risk.

Objective: The aim was to compare respiratory symptoms in nursing home residents and patients with uncontrolled asthma, who are considered vulnerable to COVID-19.

A snapshot of COVID-19 infection in patients with solid tumors.

Coronavirus disease 2019 (COVID-19) pandemic is affecting a high percentage of the population at an unprecedented rate. Cancer patients comprise a subgroup especially vulnerable to this infection. Herein, we present a prospective analysis of epidemiological, clinical, radiological and laboratory data of consecutive adult cancer patients seen in the Clínico San Carlos University Hospital (Madrid, Spain), and admitted to hospital and tested for COVID-19 between 21 February 2020 and 8 May 2020 due to clinical suspicion of infection.

Advanced characterisation of aerosol size properties from measurements of spectral optical depth using the GRASP algorithm.

This study evaluates the potential of using aerosol optical depth ( ) measurements to characterise the microphysical and optical properties of atmospheric aerosols. With this aim, we used the recently developed GRASP (Generalized Retrieval of Aerosol and Surface Properties) code for numerical testing of six different aerosol models with different aerosol loads. The direct numerical simulations (self-consistency tests) indicate that the GRASP-AOD retrieval provides modal aerosol optical depths (fine and coarse) to within 0.

Aerosol properties of mineral dust and its mixtures in a regional background of north-central Iberian Peninsula.

To broaden the knowledge about desert dust (DD) aerosols in western Mediterranean Basin, their fingerprints on optical and microphysical properties are analyzed during DD episodes in the north-central plateau of the Iberian Peninsula between 2003 and 2014. Aerosol columnar properties obtained from the AErosol RObotic NETwork (AERONET), such as aerosol optical depth (AOD), Ångström exponent (AE), volume particle size distribution, volume concentration (VC), sphericity, single scattering albedo, among others, are analyzed in order to provide a general characterization, being some of them compared to particle mass surface concentrations PM, PM, and their ratio, data obtained from EMEP network. The mean intensity of DD episodes exhibits: AOD=0.

Aerosol optical properties in Northern Norway and Svalbard.

We present comparisons between estimates of the aerosol optical thickness and the Ångström exponent in Northern Norway and Svalbard based on data from AERONET (Aerosol Robotic Network) stations at Andenes (69.28°N, 16.01°E, 379 m altitude) and Hornsund (77.

[Periungueal capillaroscopy: an easy and reliable method to evaluate all microcirculation diseases].

Periungueal capillaroscopy is a simple and reliable non-invasive technique allowing evaluation of cutaneous microcirculation. It was promoted for decades in patients with Raynaud's phenomenon in order to differentiate between the benign primary Raynaud's phenomenon and the secondary form in connective tissue diseases, especially systemic sclerosis. Nevertheless, the value of this procedure has also been shown in numerous pathologies such as diabetes or cardiovascular diseases.

Columnar and surface aerosol load over the Iberian Peninsula establishing annual cycles, trends, and relationships in five geographical sectors.

The study of atmospheric aerosol load over the Iberian Peninsula (IP) under a climatological perspective is accomplished by means of PM10 and AOD440 nm measurements from EMEP and AERONET networks, respectively, in the period 2000-2013. The PM10 annual cycles in five Iberian sectors show a main maximum in summer and a secondary maximum in spring, which is only observed in the southern area for the AOD climatology. The characteristics of PM10-AOD annual cycles of each geographical sector are explained by the different climatology of the air mass origins and their apportioning.

[High plasmatic concentration of vitamin B12: an indicator of hepatic diseases or tumors].

Purpose: To identify the diseases that are associated with a high plasma concentration of vitamin B12 and to measure the strength of this association.

Patients And Methods: Retrospective study including all admissions between 1st May, 2005 and 30th April, 2008 in the UMAG pole departments (emergency, internal medicine, acute geriatrics and medical intensive care) with a test for plasma vitamin B12. The association between each of medical information system codes (solid tumors, malignant hematologic process, and renal disease) and a high or low vitamin B12 concentration was measured by odds ratios (OR) from logistic models taking into account repeated admissions, with adjustment for age and the weighted Charlson index.

[Pulmonary embolism revealed by a seizure: a case report and literature review].

Introduction: Pulmonary embolism is a frequent disorder with a diagnostic approach based on probability estimation. Nevertheless, in some cases, prognosis may be impaired by delayed diagnosis resulting from atypical presenting manifestations.

Case Report: We report a 37-year-old woman, admitted for a seizure as the presenting manifestation of pulmonary embolism, and review nine additional similar cases reported in the literature since 1945.

Aldolase predicts subsequent myopathy occurrence in systemic sclerosis.

Introduction: Myopathy related to systemic sclerosis (Myo-SSc) is a disabling and unpredictable complication of SSc. We assessed the predictive value of serum aldolase, creatine kinase (CK), alanine transaminase (ALT), aspartate transaminase (AST) and C-reactive protein (CRP) to estimate the risk of developing Myo-SSc.

Methods: We enrolled 137 SSc patients without proximal muscle weakness in a prospective monocentric study to follow them longitudinally over a four-year period.

[Inflammatory aortitis in giant cell arteritis].

A sub-clinical inflammatory aortitis is very frequent in patients with giant cell arteritis, and can be the only localization of the disease. In most patients, this aortitis is asymptomatic and is of no consequence on the patient's survival. The relative risk of developing an aortic dissection or aneurysm is 17.

Comparative kinetic study and microwaves non-thermal effects on the formation of poly(amic acid) 4,4'-(hexafluoroisopropylidene)diphthalic anhydride (6FDA) and 4,4'-(hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline (BAPHF). Reaction activated by microwave, ultrasound and conventional heating.

Green chemistry is the design of chemical processes that reduce or eliminate negative environmental impacts. The use and production of chemicals involve the reduction of waste products, non-toxic components, and improved efficiency. Green chemistry applies innovative scientific solutions in the use of new reagents, catalysts and non-classical modes of activation such as ultrasounds or microwaves.

Serum CC chemokine ligand-18 predicts lung disease worsening in systemic sclerosis.

Elevated serum CC chemokine ligand (CCL)18 reflects lung fibrosis activity in systemic sclerosis (SSc) and could be an early marker of lung function worsening. Therefore, we sought to evaluate whether serum CCL18 levels at baseline could predict worsening of lung disease in SSc. In this prospective study, 83 SSc patients were analysed longitudinally over a 4-yr observation period for the risk of occurrence of combined deleterious events, defined as a 10% decrease from baseline of total lung capacity or forced vital capacity % predicted, or death, according to serum CCL18 at inclusion.

[Late onset Becker muscular dystrophy. A case report and literature review].

Introduction: The first manifestations of Becker's muscular dystrophy usually occur during childhood, as Duchenne's muscular dystrophy, a related disease. However, clinical presentation is usually more heterogeneous and less severe.

Case Report: We report a 54-year-old man who presented with a late onset of Becker's muscular dystrophy, and review 12 additional similar cases previously reported in the literature.

[Salmonella bredney: a rare cause of mycotic aneurysm].

Mycotic aneurysms are rare, remain asymptomatic for a long time, and may be life threatening by their rupture if therapy is delayed. Historically associated with Streptococcus pyogenes and Staphylococcus aureus, they now frequently involve Salmonella species in elderly or immunodeficient patients, and complicate vascular investigation or surgical procedures. Frequently located in the abdominal aorta, they can also be found rarely in other location.

[Peripheral neuropathy with autonomous nervous system involvement in the course of dermatomyositis].

A peripheral neuropathy occurs rarely during the course of an inflammatory myopathy. Once the classical aetiologies of peripheral neuropathies are ruled out, the diagnosis of neuromyositis can be accepted. We report a patient with dermatomyositis who presented a peripheral neuropathy revealed by dysautonomia.