Statin use and peripheral nerve function-A prospective follow-up study.

Purpose: To examine the association between use of statins and risk of deterioration of peripheral nerve function.

Methods: We prospectively followed patients who initiated statin treatment and compared them with statin never-users (non-users). At the time of inclusion and at 1-year follow-up, participants underwent tests for peripheral nerve function (ie nerve conduction studies, quantitative sensory testing), skin biopsies and ratings of symptoms and signs of neuropathy.

Statins and polyneuropathy revisited: case-control study in Denmark, 1999-2013.

Aim: In a previous study, we found a positive association between statin use and polyneuropathy risk. Other studies reported equivocal results. The present study aimed to confirm our findings with a design similar to that used in our previous study but with a larger data set.