Clinical Knowledge Model for the Prevention of Healthcare-Associated Venous Thromboembolism.

Knowledge models inform organizational behavior through the logical association of documentation processes, definitions, data elements, and value sets. The development of a well-designed knowledge model allows for the reuse of electronic health record data to promote efficiency in practice, data interoperability, and the extensibility of data to new capabilities or functionality such as clinical decision support, quality improvement, and research. The purpose of this article is to describe the development and validation of a knowledge model for healthcare-associated venous thromboembolism prevention.

Endometrial Receptivity Analysis - a tool to increase an implantation rate in assisted reproduction.

Introduction: A successful embryo implantation is crucial for a positive outcome of in vitro fertilization. But there is only a short period during which the endometrium is receptive for embryo, this so called implantation window can be detected by a molecular diagnostic method endometrial receptivity analysis (ERA).

Objective: To find out the percentage of patients with a non-receptive endometrium in the time of ERA and to learn what part of them got pregnant after the identification of their personalized implantation window.

Post fire organic matter biodegradation in permafrost soils: Case study after experimental heating of mineral horizons.

Periodical ground fires of high frequency in permafrost forest ecosystems of Siberia (Russian Federation) are essential factors determining quantitative and qualitative parameters of permafrost soil organic matter. Specific changes in physical and chemical parameters and microbial activity of permafrost soil mineral horizons of northern taiga larch stands were revealed after heating at high temperatures (150-500°C) used for imitation of different burn intensities. Burning at 150-200°C resulted in decreasing of soil pH, whilst heating at 300-500°C caused increase of pH compare to unheated soils.

[Postfire restoration of organic substance in the ground cover of the larch forests in the permafrost zone of central Evenkia].

The role of ground fires in transformation of organic substances in the ground cover of larch stands in the permafrost zone of Central Siberia was studied, as was the postfire restoration dynamics of organic substances. Ground fires lead to a considerable decrease in concentrations and resources of organic carbon and its individual fractions in the ground cover, and restoration takes many decades.

Optical nanosensor platform operating in near-physiological pH range via polymer-brush-mediated plasmon coupling.

The nanosensors' platform made of a stimuli-responsive polymer/noble metal nanoparticle composite thin film exploits the combination of the swelling-shrinking transition in a poly(N,N'-dimethylaminoethyl methacrylate) brush and the localized surface plasmon resonance in metal nanoparticles to enable the transduction of changes in the solution pH in the near-physiological range into a pronounced optical signal.

Implementation of a two-specimen requirement for verification of ABO/Rh for blood transfusion.

Background: This study presents our implementation of a two-specimen requirement with no prior record of ABO/Rh to verify patients' blood type before transfusion.

Materials And Methods: Blood type verification was introduced, discussed, approved, and implemented over a 12-month period (May 2007 to May 2008). Potential barriers and impact on benchmark indicators were identified and tracked.

Gold-nanoparticle-enhanced plasmonic effects in a responsive polymer gel.

Localized surface plasmon resonance excited in gold nanoparticles coupled with a responsive polymer gel is explored. A specially designed structure (vertically aligned cylindrical pores decorated with gold nanoparticles) of responsive polymer gel thin films allows for the transduction of external signal/ stimuli into a strong optical effect enhanced by interactions of gold nanoparticles.

Ultrathin molecularly imprinted polymer sensors employing enhanced transmission surface plasmon resonance spectroscopy.

An ultrathin novel nanosensor (31.5 +/- 4.1 nm thick in the absence of analytes), employing a molecularly imprinted polymer as a recognition element for cholesterol and gold nanoparticle enhanced transmission surface plasmon resonance spectroscopy for detection, was constructed.

Nanosensors based on responsive polymer brushes and gold nanoparticle enhanced transmission surface plasmon resonance spectroscopy.

Swelling (and shrinking) of poly(2-vinylpyridine), P2VP, polymer brushes, caused by pH changes, could be readily monitored by transmission surface plasmon resonance, T-SPR, spectroscopy. Gold nanoparticles attached to the P2VP polymer brushes dramatically enhanced the pH-induced shift in the T-SPR absorption spectra. (A 50 nm shift of the absorption maximum of the T-SPR spectrum of the supporting gold nanoislands was observed upon changing the pH from 5.

Hybridization of oligonucleotide-modified silver and gold nanoparticles in aqueous dispersions and on gold films.

Functionalization of silver and gold nanoparticles by 12mer-thiolated homo-oligonucleotides, SA and ST (containing only adenine or thymine, respectively), and their hybridization and dehybridization in aqueous dispersions have been described. In addition, ST and SA were self-assembled onto gold films and hybridized with their complementary pairs, unlabeled or labeled by gold and silver nanoparticles. The base pairing between DNA strands and the types of oligonucleotides (adenine or thymine) attached to the nanoparticles was detected by Polarization Modulated Fourier Transform Infrared Reflection Absorption Spectroscopy (PM-FTIRRAS).

[Rhythmic photostimulation and a number of alpha-rhythm dipoles in the human brain].

Dynamic study of the equivalent current dipoles (ECDs) of alpha rhythm in the human brain was performed in a one-dipole model. The number of ECDs was shown to be dependent on the time course of visual stimulation, on the phase shift of triggering of flickers with alpha-rhythm frequency from alpha-wave, as well as on the type of visual illusions produced in subjects by this stimulation. The data are discussed in accordance with the "scanning hypothesis" that predict a certain functional meaning of the spreading alpha-wave for cortical processing of sensory information in the human brain.