Exercise Preconditioning of the Donor Liver Decreases Cold Ischemia/Reperfusion Injury in a Mouse Model.

Background: Liver transplantation stands as the primary treatment for end-stage liver disease, with demand surging in recent decades because of expanded indications. However, hepatic ischemia/reperfusion injury can lead to liver transplant failure in both deceased donor and living donor transplantation. This study explored whether preconditioning donor livers through exercise training (ExT) could mitigate cold ischemic injury posttransplantation.

ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia-Reperfusion Injury and the Progression of Hepatic Metastases.

Background: Exercise can promote sustainable protection against cold and warm liver ischemia-reperfusion injury (IRI) and tumor metastases. We have shown that this protection is by the induction of hepatic mitochondrial biogenesis pathway. In this study, we hypothesize that ZLN005, a PGC-1α activator, can be utilized as an alternative therapeutic strategy.

Clinical image quality assessment and mean glandular dose for full field digital mammography.

This study aims to assess the image quality (IQ) of 12 mammographic units and to identify units with potential optimisation needs. Data for 350 mammography examinations meeting inclusion criteria were collected retrospectively from April 2021 to April 2022. They were categorised based on the medical reports into 10 normal cases, 10 cases displaying calcifications and 10 cases presenting lesions.

Intraluminal Duodenal Diverticulum: A Rare Cause of Chronic Epigastric Pain.

Despite its first identification in 1885, intraluminal duodenal diverticulum remains a rare entity and only a few case reports are found in the literature. Its diagnosis is almost always delayed due to the lack of specific symptoms and to the very vague presentation consisting of mild epigastric discomfort. However, with the aid of new diagnostic modalities and imaging, it has become easier to diagnose this entity when its symptoms persist.

Total or Subtotal Colectomy with Primary Anastomosis for Occlusive Left Colon Cancer: A Safe, Acceptable and Applicable Procedure.

Introduction: Occlusive left colon cancer is a major emergency setting in colon cancer with high morbidity and mortality rates. Different surgical treatment exist since there is no clear guidelines for the best treatment. We have conducted this retrospective study in order to evaluate the safety, morbidity, and bowel movement status of the operated patients.

Sporadic colon cancer in Lebanon: A clinicopathological study.

Colon cancer is a heavy public health burden. No data has been previously published on colon cancer epidemiology in Lebanon. The objective of this study was to report the clinical and pathological features of surgically operated colon cancer.

[Colorectal cancer in young patients: presentation, clinicopathological characteristics and outcome].

Unlabelled: Previous studies have emphasized the increasing incidence of colorectal cancer (CCR) among young adults and suggest that they may have more aggressive disease and worse five-year survivals than their older counterparts.

Purpose: Describe the profile of sporadic colorectal cancer in young patients focusing on its prevalence, clinicopathological characteristics, prognostic and survival factors.

Methods: Three hundred and twenty-five CCR patients were divided in two groups : G1 < 45 years and G2 > 45 years.

[Subtotal or total colectomy as surgical treatment of left-sided occlusive colon cancer].

Introduction: The treatment of acutely obstructed carcinoma of the left colon and sigmoid still represents a matter of controversy. The aim of this study was to assess retrospectively the results of its management by emergency subtotal or total colectomy with primary anastomosis.

Materials And Results: Sixty-seven patients were reviewed.

Unusual etiology of epigastric pain.

Background: Epigastric pain is a common presenting complaint encountered in urgent care settings. Although peptic, biliary, and pancreatic pathologies are the most frequent findings, other rare diagnoses also can be found.

Objectives: We report an unusual case of acute epigastric pain in which abdominal ultrasound was of great support in revealing the diagnosis.

[Value of US imaging following mastectomy].

Purpose: To assess the value of US of the mastectomy site at the time of follow-up of the contralateral residual breast.

Materials And Methods: Over a 5 year period, 251 patients with previous mastectomy underwent 505 unilateral mammographies with US of the mastectomy site. The time delay between imaging and mastectomy ranged between 1-15 years, with a mean of 7.

The impact of obesity on surgical outcome after pancreaticoduodenectomy.

Context: The effect of obesity on surgical outcome is becoming an increasingly relevant issue given the growing rate of obesity worldwide.

Objective: To investigate the specific impact of obesity on pancreaticoduodenectomy.

Design: A retrospective comparative study of a prospectively maintained database was carried out to investigate the specific impact of obesity on the technical aspects and postoperative outcome of pancreaticoduodenectomy.

Is therapy with calcium and vitamin D and parathyroid autotransplantation useful in total thyroidectomy for preventing hypocalcemia?

Background: Routine calcium and vitamin D administration and routine autotransplantation of parathyroid glands can prevent hypocalcemia after total thyroidectomy.

Methods: Routine autotransplantation of 1 or more parathyroid glands and oral calcium and vitamin D supplementation was used in 252 patients.

Results: One, 2, or 3 parathyroid glands were autotransplanted in 223, 27, and 2 patients, respectively.

[Retroperitoneal cystic lymphangiomas in adults: four case reports and review of the literature].

Retroperitoneal location of cystic lymphangiomas in adult patients is rare. Their clinical presentation is not specific. Magnetic resonance imaging is the best radiological exam for the diagnosis.

Enlarged parathyroid glands discovered in normocalcemic patients during thyroid surgery.

Background: This is a retrospective study analyzing data of normocalcemic patients with enlarged parathyroid glands discovered during thyroid surgery and comparing it with data of patients operated on for proved primary hyperparathyroidism.

Methods: The records of patients with enlarged parathyroid glands (group 1) and those with primary hyperparathyroidism (group 2) were reviewed.

Results: There were 11 patients in group 1 and 123 patients in group 2.

One hundred liver resections: improved outcome in a tertiary care center in Lebanon.

Background: Recent reports highlight the reduced mortality and morbidity rates of liver resection in the last decades. The authors report on the surgical techniques and perioperative management that have yielded a low mortality and morbidity rates.

Methods: One hundred consecutive liver resections carried out from 1997 to 2005 were reviewed.

Extra-adrenal composite pheochromocytoma-ganglioneuroma.

Composite tumors containing pheochromocytoma and ganglioneuroma are rare tumors typically arising in the adrenal glands. Very few were reported outside of the adrenals. We present the case of a middle-aged woman with a retroperitoneal mass that was discovered when she complained of local signs of compression and systemic signs of catecholamine hypersecretion.

Prevalence and risk factors for primary hyperparathyroidism in hyperthyroid patients.

Background: Coexistence of hyperthyroidism and primary hyperparathyroidism may be more prevalent than previously recognized. We report 13 cases of concomitant occurrence of both diseases to estimate their combined prevalence and its factors.

Methods: Ninety-six unselected patients admitted for elective hyperthyroidism surgery were retrospectively included.

Existence and anatomic distribution of double parathyroid adenoma.

Background: Double parathyroid adenomas occur in 2% to 15% of primary hyperparathyroidism cases, but the very existence of double adenomas has been controversial. This study was conducted to evaluate the clinical significance and anatomic distribution of parathyroid double adenomas.

Study Design: Mono-institutional retrospective study of the medical records of 183 unselected consecutive patients who underwent intervention for primary hyperparathyroidism between 1996 and 2003.