Publications by authors named "Togay-Isikay C"

Introduction: Extracranial internal carotid stenosis (EICS) is a well-established cause of stroke. Carotid near-occlusion (CNO), either distally collapsed or not, is a rare sub-type of EICS with conflicting data regarding the necessity for treatment. The aim of this study is to evaluate the results of carotid artery stenting (CAS) for patients with symptomatic CNOs.

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Objective: Besides its morbidity and mortality all over the world, SARS-CoV-2 infection maintains its importance with prolonged symptoms after acute disease. The post-infectious period including a heterogeneous group of symptoms is named . This study aimed to describe persisting symptoms three months after COVID-19 and risk factors associated with .

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Background & Aims: There is a change in the mass and composition of paretic and non-paretic skeletal muscles in the chronic phase of stroke. The multi-center, prospective, and observational Muscle Assessment in Stroke Study (MASS) was performed to evaluate the degree of muscle loss during the in-hospital acute stroke setting and determine factors contributing to this loss.

Methods: Acute dysphagic ischemic stroke patients (n = 107) admitted to neuro-intensive care units were evaluated by computed tomography on days 1 and 14 after admission to determine the cross-sectional muscle area (CSMA) at the level of the mid-humerus, mid-thigh, and third lumbar vertebra.

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Primary Objective: The optimal treatment adherence rate among patients with stroke is low. This study aims to determine the effect of clinical pharmacists' intervention on treatment adherence and quality of life (QOL) in patients with first-ever stroke.

Research Design: This open, controlled, prospective and interventional study was conducted sequentially at two different university hospitals for 3 months.

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Background: Non-invasive vagus nerve stimulation (nVNS) using a hand-held stimulator placed on the neck is an FDA-approved treatment for primary headache disorders. The safety of nVNS is unknown in stroke patients.

Objective: To assess the safety and feasibility of nVNS for the acute treatment of stroke.

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Article Synopsis
  • The study investigates the link between renal function and markers of cerebral small vessel disease in patients with acute ischemic stroke or transient ischemic attack.
  • Impaired renal function is associated with a higher number of brain lesions and an increased overall burden of small vessel disease, making it an independent risk factor for certain stroke types.
  • Findings suggest that renal impairment is linked to specific stroke etiologies, particularly small vessel occlusion, and underscores the importance of monitoring renal health in stroke patients.
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The classically affected cranial nerve from intracranial hypertension is the sixth nerve. Carcinomatous meningitis can cause persistent or progressive cranial nerve palsies by infiltrating them in the subarachnoid space. Here we present a rare case of episodic, short-lasting, and unilateral oculomotor nerve palsy associated with carcinomatous meningitis and intracranial hypertension in a 44-year-old woman diagnosed with metastatic lung adenocarcinoma.

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Purpose: Migraine is thought to be a neurovascular disorder and increases the likelyhood to develop ischemic complications. Studies have shown that vascular disorders such as ischemic optic neuropathy, retinal artery and vein obstructions are more common in patients with migraine. This study aimed to evaluate the differences between retinal and optic disc microvasculature between migraine patients with and without aura and healthy controls using optical coherence tomography angiography (OCTA) imaging.

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Article Synopsis
  • Unhealthy lifestyles and poorly managed vascular risk factors significantly contribute to stroke incidents and outcomes.
  • A study of 787 ischemic stroke patients showed that nearly 49% had four or more modifiable risk factors that could have been optimized to prevent strokes.
  • Key predictors for preventable strokes included younger age, female gender, and certain types of artery issues, highlighting the need for targeted strategies in risk factor management.
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  • The study aimed to compare MRI findings in patients with primary and secondary pseudotumor cerebri (PTC) to assess their diagnostic value and link them with symptoms and lab results.
  • Twenty-eight PTC patients were evaluated alongside a control group of 20 people, using the Modified Dandy Criteria for diagnosis and extensive MRI assessments.
  • Key MRI markers identified included posterior flattening of the globe and optic nerve sheath distention, which showed high specificity, making them significant indicators for diagnosing PTC.
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This case with unilateral complete blepharoptosis and slight limitation of upgaze as ocular findings due to midbrain infarction represents an unusual form of intra-axial oculomotor nerve involvement. A 65-year-old man was admitted with acute unilateral ptosis of the left eyelid and gait ataxia. He had chronic hypertension in the medical history.

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We present three patients with Behçet's disease associated with intracardiac thrombus and pulmonary vascular involvement. One of these patients had also Budd-Chiari syndrome. All patients were treated with corticosteroid plus monthly intravenous cyclophosphamide as first line treatment and with no recurrences.

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We present a case of transient ischemic attack (TIA) as an extremely rare presentation of cerebral vein thrombosis. A 41-year-old man presented with a headache and episodes of hypoesthesia on his left side lasting approximately 30 minutes. Several vascular risk factors were remarkable in his medical history.

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Background: The pronation test reveals slight paresis in the upper limbs. Patients hold their arms outstretched in front of them with the hands supinated while they keep their eyes closed. Position changes such as pronation, abduction, or drift indicate a positive pronation test.

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We report a series of four cases presented with transient ischemic attacks (TIA) or ischemic stroke as the predominant manifestation of neurobrucellosis (NB). Three of the patients were 20-28 years of age, and one patient was 53 years old. They all used to consume unpasteurized milk or its products.

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Although abnormalities in course and geometry (tortuosity, kinking, and coiling) of the internal carotid arteries (ICA) are commonly identified, their etiology and relationship with stroke and stroke risk factors remain unclear This study assessed the clinical and ultrasonographic features of the patients with abnormalities in course and geometry of the ICA. Carotid color duplex ultrasound studies of 345 consecutive patients referred to the Neuroultrasound Lab were prospectively evaluated. Abnormalities in direction and course of the ICA were classified according to the criteria of Weibel-Fields and Metz modified by the authors.

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We present a case of a 25-year-old woman with drowsiness, nystagmus, severe ataxia and areflexia, which developed six weeks after admission to an obstetric clinic for hyperemesis gravidarum. She had been treated with intravenous dextrose and electrolyte solutions and antiemetics. Magnetic resonance imaging (MRI) performed on the fifth day of her neurologic symptoms showed increased intensity in both thalami, periaqueductal grey matter, the floor of the fourth ventricle and superior cerebellar vermis in T2 weighted and FLAIR images.

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