Publications by authors named "Togashi S"

Objective: To investigate whether segmental phase angle (PhA) is a useful predictor of severe chronic obstructive pulmonary disease (COPD) exacerbation.

Research Methods And Procedures: This prospective cohort study enrolled consecutive patients with COPD with a follow-up period of 3 years. The primary outcome was incidence of severe exacerbation.

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Informal caregiving can impair caregivers' subjective well-being. However, this issue has been overlooked among young adults. We examined the association between informal caregiving and subjective well-being among young adults in Japan.

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Background: The number of patients with heart failure (HF) is rapidly increasing as palliative care is being integrated into HF management and the need for a nursing workforce to meet these demands grows. To address this, we have developed a Web-based educational program on primary palliative care for HF among general registered nurses caring for patients with HF in Japan.

Objective: The aim of this study was to evaluate the program's effectiveness on nurse-reported palliative care practice, difficulty, and knowledge.

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Article Synopsis
  • Early intervention through mechanical thrombectomy (MT) for patients with large vessel occlusion (LVO) can improve outcomes, but effective prehospital detection and transport strategies were lacking before this study.
  • The study analyzed the implementation of an emergent large vessel occlusion (ELVO) screening system by emergency medical services (EMS) in Akita, Japan, and its effects on patient transport times to MT-capable hospitals.
  • Results showed that the triage group experienced shorter transport times with a notable 14-minute reduction in one hospital, and the ELVO screen had a sensitivity of 87% for accurately identifying LVO cases.
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The basket-weave method is an orbicularis oris muscle reconstruction method used in primary unilateral cleft lip repair. We compared the long-term results of the basket-weave method with those of a conventional method. For primary unilateral cleft lip repair, we compared the long-term results of 7 cases in which the orbicularis oris muscle was reconstructed by use of the basket-weave method, and of 7 cases in which the reconstruction was performed by use of the conventional method.

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Aim: To support informal caregivers, a simple assessment tool capturing the multidimensional nature of caregiving experiences, including negative and positive aspects, is required. We developed a short form of the Japanese version of the Caregiver Reaction Assessment (CRA-J), a multidimensional assessment scale for caregiver experiences.

Methods: The internet survey involved 934 Japanese informal caregivers aged 20-79 years (mean age = 58.

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Article Synopsis
  • A study was conducted on 467 hospitalized patients aged 65 and older with dysphagia to explore the prevalence of polypharmacy (taking 5 or more medications) and the use of potentially inappropriate medications (PIMs) based on updated guidelines.
  • *Out of 399 participants analyzed, it was found that 67.7% experienced polypharmacy and 56.1% were on PIMs, but these factors did not show a significant impact on patients' swallowing function at discharge.
  • *The study highlights the necessity for healthcare providers to regularly review and assess the appropriateness of medications for older patients to ensure better management and outcomes.
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To describe aggressive treatments at end-of-life among inpatients with cancer and non-cancer diseases and to evaluate factors associated with these treatments using the Japanese national database (NDB). We conducted a retrospective cohort study among inpatients aged ≥ 20 years who died between 2012 and 2015 using a sampling dataset of NDB. The outcome was the proportion of aggressive treatments in the last 14 days of life.

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Background: Because the penetration of transvenous lead extraction (TLE) for cardiac implantable electronic device (CIED) infection has not been investigated in Japan, we conducted a population-based, retrospective, descriptive study to evaluate regional disparities in the use of TLE for CIED infection and the potential undertreatment of CIED infection using a nationwide insurance claims database.

Methods and results: Patients who underwent CIED implantation or generator exchange and TLE between April 2018 and March 2020 were identified. Moreover, the penetration ratio of TLE for CIED infection in each prefecture was estimated.

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Article Synopsis
  • The study investigates the effectiveness of using claims data to determine causes of death for end-of-life patients in Japan, addressing the lack of validity surrounding this method.
  • A comparison was made between claims data and death certificates for patients who died between 2018 and 2019, focusing on nine causes of death, including cancer.
  • The findings show high accuracy for identifying cancer and cerebrovascular disease using specific data combinations, while results for other causes of death were less reliable due to smaller sample sizes.
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  • The study evaluated the effectiveness of body mass index (BMI) in diagnosing sarcopenic dysphagia among 467 patients with dysphagia, using a reliable diagnostic algorithm.
  • Approximately 61.7% of the patients were diagnosed with sarcopenic dysphagia, and the diagnostic accuracy of BMI was measured with an area under the curve (AUC) of 0.60-0.62 across various groups.
  • It was concluded that a BMI of less than 20.0 kg/m2 could serve as a strong indicator for sarcopenic dysphagia, suggesting that healthcare providers should screen for this condition in patients presenting with dysphagia and low BMI.
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Introduction: There are few studies have conducted digital breast tomosynthesis (DBT) in addition to digital mammography (2DDM) and ultrasound (US) for screening. The purpose of this study is to determine the possibility of synergistic effects of DBT and US screening for Japanese.

Methods: 5023 examinations of the opportunistic screening using 2DDM and US (2D group: 2581) or 2DDM and US plus DBT (3 group: 2442) were performed at our facility from May 1, 2017 to March 31, 2019.

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Complex intracranial aneurysms remain challenging to treat using standard microsurgical or endovascular techniques. These aneurysms often require a combination of deconstructive and reconstructive procedures, such as parent artery occlusion, flow alteration, and blind-alley formation with or without bypass surgery, for effective and enduring therapeutic effects. It is important to determine the type of bypass based on the site of occlusion of the patent artery, anatomical features of the distal vessels, and expected adequate blood flow.

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Objectives: In recent years, many studies have reported that the presurgical nasoalveolar molding method improves the nose morphology; however, the reason for its effectiveness after surgery has never been understood. We evaluated the effect of nasoalveolar molding by comparing it with a passive orthopedic method without a nasal stent and focusing on the nostril morphology after primary cheiloplasty using various measurement methods. We then analyzed the essential factors.

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[Purpose] In Japan, the government issued a state of emergency due to the spread of COVID-19 in April 2020. In this study, we measured physical activity before and after the state of emergency, and assessed the factors that affected physical activity. [Participants and Methods] We included thirteen elderly people living in Hiroshima Prefecture, Japan, in the study.

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Background: The purpose of this study is to confirm the position of DBT in breast cancer screening in Japan, to assess cancer detection rates, recall rates, positive predictive value (PPV), and to evaluate the type of mammographic findings of cancer with the use of digital mammography alone (2DDM) and combined with digital breast tomosynthesis (DBT).

Methods: 11,894 examinations of the opportunistic breast cancer screening using only 2DDM and 2DDM plus DBT were performed from May 1, 2017 to March 31, 2019. The 11,894 women [3535 women who received DBT in addition to 2DDM (3D group) and 8359 who received 2DDM only (2D group)] participated in this study.

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Cerebral hyperperfusion syndrome (HPS) is a rare complication of carotid endarterectomy (CEA) and stenting. There are only a few case reports about HPS after intracranial stenting, and its clinical course remains unclear. We report an unusual case of HPS after intracranial internal carotid artery (ICA) stenting.

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Background: Recurrent hydrocephalus may occur as a complication of neurosarcoidosis with chronic inflammation. We present a case that required a combination of multistage endoscopic diversion of the cerebrospinal fluid pathway and shunt surgery.

Case Description: A 34-year-old man presented with progressive nausea and vomiting.

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Background: Growing teratoma syndrome(GTS)is the progression of a mature teratoma during or following radiochemotherapy for germ cell tumors. We report two surgical cases of GTS. CASE 1: A 24-day-old new-born presented with vomiting and head enlargement.

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The failure of Kupffer cells (KCs) to remove endotoxin is an important factor in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In this study, the effects of exercise training on KC function were studied in terms of in vivo endotoxin clearance and inflammatory responses. Mice were allocated into rest and exercise groups.

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Objective: The objective of this study was to examine whether fractional exhaled nitric oxide (FeNO) and spirometry can be used as indices to evaluate adverse health effects of low-concentrated chemical inhalation exposure, mainly to formaldehyde.

Methods: Thirty-three subjects (pathology technicians) and 30 controls (workers without handling any chemicals in the same hospitals) participated in this study. All participants underwent FeNO measurement and spirometry before and after 5 days of work.

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Colistin is an antimicrobial cationic peptide that belongs to the polymyxin family. Colistin was clinically used for the treatment of gram-negative infections but fell out of favour because of its significant side effects including neurotoxicity and nephrotoxicity. More recently, colistin has been regarded as one of the important options for nosocomial infections caused by multidrug resistant bacteria.

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Progressive cerebral infarction in patients with hemorrhagic onset of moyamoya disease is rare, and a treatment strategy is not well established. Here, we report a case that was successfully treated with emergency bypass surgery. A 58-year-old woman presented with a sudden disturbance of consciousness and right-sided hemiparesis.

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The effects of chronic administration of piceatannol-enriched (9.5% w/w) passion fruit seed extract (PFSE) on the cardiovascular damage induced in a high-fat (HF) diet-fed model of Fischer 344 rats were evaluated. Rats were fed the control, HF, or HF diets containing PFSE (0.

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