Parenteral nutrition compatibility and stability: Practical considerations.

Parenteral nutrition (PN) is a complex preparation that contains multiple component products with the associated risk for incompatibilities and diminished stabilities when combined together as an admixture. Significant patient harm can result from prescribing, preparing, and administering PN without confirming compatibility and stability. Incompatibility or instability is rarely obvious to the unaided eye, so safe PN admixture relies on incorporating physicochemical properties of the included components into compatibility and stability decisions.

Changes in serum prealbumin as a marker for nitrogen balance in surgical oncology patients.

Background: Serum prealbumin has long been used as a marker of nutritional status. However, prealbumin is a negative acute phase reactant influenced by several non-nutritional-related factors including surgery, infection, and cancer. An increasing prealbumin has been correlated with a positive nitrogen balance in general surgery patients receiving parenteral nutrition (PN) with 88% specificity and 70% sensitivity.

Significant Published Articles in 2022 for Pharmacy Nutrition Support Practice.

The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2022 considered important to their clinical practice. The citation list was compiled into a spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Significant Published Articles in 2021 for Pharmacy Nutrition Support Practice.

The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2021 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Safe care transitions for patients receiving parenteral nutrition.

Transitions of care require coordination between inpatient healthcare providers, care managers, outpatient/ambulatory providers, and the patient/caregiver and family members. Poor communication during transitions of care can affect health outcomes and economic costs for patients/caregivers, healthcare providers, and healthcare systems. The goal of this paper is to identify risk-prone processes in the transition of care for patients requiring parenteral nutrition (PN) between healthcare environments, including the hospital, home, skilled nursing facility, and long-term acute care hospital settings.

Significant Published Articles in 2020 for Pharmacy Nutrition Support Practice.

The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2020 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Subtherapeutic posaconazole prophylaxis in a gastric bypass patient following hematopoietic stem cell transplantation.

Purpose: A case of invasive fungal infections (IFIs) with subtherapeutic posaconazole prophylaxis in a gastric bypass patient following hematopoietic stem cell transplantation (HSCT) is reported.

Summary: A 52-year-old malnourished male with a medical history of Roux-en-Y gastric bypass for obesity developed acute myelogenous leukemia and underwent allogeneic HSCT approximately 17 months later. He was admitted 1 month after HSCT for failure to thrive and initiated on parenteral nutrition due to worsening diarrhea and suspected gastrointestinal graft-versus-host disease (GI GVHD).

Significant Published Articles for Pharmacy Nutrition Support Practice in 2019.

The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2019 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Significant Published Articles for Pharmacy Nutrition Support Practice in 2018.

The purpose of this article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2018 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Significant Published Articles for Pharmacy Nutrition Support Practice in 2017.

The purpose of the article is to assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2017 considered important to their clinical practice. The citation list was compiled into a spreadsheet where the author participants were asked to assess whether the article was considered important to nutrition support pharmacy practice.

Significant Published Articles for Pharmacy Nutrition Support Practice in 2016.

To assist the pharmacist engaged in nutrition support therapy in staying current with pertinent literature. Several clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2016 considered important to their clinical practice. The citation list was compiled into a single spreadsheet where the author participants were asked to assess whether the paper was considered important to nutrition support pharmacy practice.

Significant Published Articles for Pharmacy Nutrition Support Practice in 2014 and 2015.

Purpose: To assist the pharmacy clinician engaged in nutrition support in staying current with the most pertinent literature.

Methods: Several experienced board-certified clinical pharmacists engaged in nutrition support therapy compiled a list of articles published in 2014 and 2015 that they considered to be important to their practice. Only those articles available in print format were considered for potential inclusion.

Bleeding Associated With Feeding Tube Placement in Critically Ill Oncology Patients With Thrombocytopenia.

Background: Existing trials have not evaluated the feasibility of oral or nasal feeding tube (FT) placement in the critically ill thrombocytopenic oncology population. Thrombocytopenia (TCP) may be considered a contraindication to FT placement due to the potential risk of bleeding complications.

Methods: Medical intensive care unit (ICU) adult oncology patients with attempted nasal or oral FT placement were evaluated in a 52-bed ICU at a comprehensive cancer center.

Significant publications for pharmacy nutrition support practice in 2013.

Purpose: To assist the pharmacy clinician engaged in nutrition support in staying current with the most pertinent literature.

Methods: Several experienced board-certified clinical pharmacists in nutrition support compiled a list of publications published in 2013 that they considered to be important to their practice. The citation list was compiled into a Web-based survey whereby pharmacist members of the American Society for Parenteral and Enteral Nutrition (A.

Stress-related mucosal bleeding in critically ill oncology patients.

Objective: To determine the incidence of stress-related mucosal bleeding (SRMB) in a critically ill oncology population receiving stress ulcer prophylaxis (SUP) with either a histamine-2 receptor antagonist (H2RA) or proton pump inhibitor (PPI).

Design: Single-center, prospective, observational study.

Setting: Fifty-two bed medical-surgical intensive care unit of an academic oncology institution.

Etomidate use for Cushing's syndrome caused by an ectopic adrenocorticotropic hormone-producing tumor.

Objective: To report the preparation and use of etomidate in a patient with Cushing's syndrome caused by an ectopic adrenocorticotropic hormone (ACTH)-producing tumor.

Case Summary: A 73-year-old man with a 5 year history of prostate cancer was admitted for symptoms consistent with Cushing's syndrome. He was started on oral metyrapone for elevated serum cortisol, ACTH, and 24 hour urinary unbound cortisol levels.

Possible pentostatin-induced symptomatic hyponatremia.

Pentostatin is an adenosine deaminase inhibitor used in the treatment of hairy cell leukemia and T-cell lymphomas. A 27-year-old man with refractory cutaneous T-cell lymphoma developed severe hyponatremia 3 days after completing his first cycle of pentostatin therapy. Shortly after hospital admission, he became disoriented and was admitted to the medical intensive care unit and treated with a combination of hypertonic saline, intravenous diuretics, and fluid restriction to reestablish normal sodium homeostasis.

Parenteral nutrition safe practices: results of the 2003 American Society for Parenteral and Enteral Nutrition survey.

Background: The American Society for Parenteral and Enteral Nutrition (A.S.P.