Can magnetic resonance-ultrasound fusion biopsy improve cancer detection in enlarged prostates?

Purpose: Patients with an enlarged prostate and suspicion of prostate cancer pose a diagnostic dilemma. The prostate cancer detection rate of systematic 12-core transrectal ultrasound guided biopsy is between 30% and 40%. For prostates greater than 40 cc this decreases to 30% or less.

Laparoscopic warm renal ischemia in the solitary porcine kidney model.

Objectives: To determine the effect of a laparoscopic approach on warm renal ischemia in the pig with a solitary kidney. Although the maximal safe duration for warm ischemia during open partial nephrectomy is commonly accepted to be 30 minutes, the maximal safe ischemic time during laparoscopic partial nephrectomy has not been previously determined.

Methods: Sixteen farm pigs underwent unilateral laparoscopic right nephrectomy.