Publications by authors named "Todd Ellerin"
Aseptic Neutrophilic Meningitis With Hypoglycorrhachia Following a Single Ocrelizumab Infusion.
Neurol Neuroimmunol Neuroinflamm
September 2021
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Science
December 2010
Article Synopsis
- Researchers conducted a genome-wide association study focusing on HIV-1 controllers and progressors to understand genetic factors influencing chronic viral infections.
- They discovered over 300 significant single-nucleotide polymorphisms (SNPs) specifically within the major histocompatibility complex (MHC), emphasizing its importance for infectious diseases.
- Key findings indicate that specific amino acids in HLA proteins, especially HLA-B and HLA-C, significantly influence the interaction between HLA and viral peptides, affecting the control of HIV infection.