Publications by authors named "Tobias R Shipley"
Article Synopsis
- - Neutrophils play a crucial role in fighting infections, but their function in drug-resistant infections, like leishmaniasis, is not well understood.
- - Research shows that drug-resistant parasites change the expression of certain neutrophil genes, increasing detoxification processes and reducing cytokine production, particularly impacting a chemokine called CCL3.
- - Reduced CCL3 levels hinder neutrophils’ ability to recruit other immune cells, which was confirmed in mouse models, highlighting how drug-resistant parasites can alter immune responses in infected skin.
