-Succinyltransferase Encoded by a Cryptic Siderophore Biosynthesis Gene Cluster in Modifies Structurally Distinct Antibiotics.

The antibiotic desertomycin A and its previously undescribed inactive -succinylated analogue, desertomycin X, were isolated from sp. strain YIM 121038. Genome sequencing and analysis readily identified the desertomycin biosynthetic gene cluster (BGC), which lacked genes encoding acyltransferases that would account for desertomycin X formation.