PSMA Accumulation in Lower Extremity Lymphedema and Hydrocele.

The development of radiolabeled small-molecule prostate-specific membrane antigen (PSMA) inhibitors has advanced molecular imaging in prostate cancer. The use of 177Lu-PSMA is especially beneficial because its therapeutic β-emission combined with γ-radiation enables precise treatment and comprehensive imaging in patients with prostate cancer. We present a case of a prostate cancer patient who developed lower extremity lymphedema and hydrocele secondary to prior radiotherapy.

Skinly: A novel handheld IoT device for validating biophysical skin characteristics.

Background: Recent advancements in artificial intelligence have revolutionized dermatological diagnostics. These technologies, particularly machine learning (ML), including deep learning (DL), have shown accuracy equivalent or even superior to human experts in diagnosing skin conditions like melanoma. With the integration of ML, including DL, the development of at home skin analysis devices has become feasible.

Exclusion of Axionlike-Particle Cogenesis Dark Matter in a Mass Window above 100 μeV.

We report the results of Phase 1b of the ORGAN experiment, a microwave cavity haloscope searching for dark matter axions in the 107.42-111.93  μeV mass range.

Dark matter axion search using a Josephson Traveling wave parametric amplifier.

We describe the first implementation of a Josephson Traveling Wave Parametric Amplifier (JTWPA) in an axion dark matter search. The operation of the JTWPA for a period of about two weeks achieved sensitivity to axion-like particle dark matter with axion-photon couplings above 10-13 Ge V-1 over a narrow range of axion masses centered around 19.84 µeV by tuning the resonant frequency of the cavity over the frequency range of 4796.

Search for a Dark-Matter-Induced Cosmic Axion Background with ADMX.

We report the first result of a direct search for a cosmic axion background (CaB)-a relativistic background of axions that is not dark matter-performed with the axion haloscope, the Axion Dark Matter eXperiment (ADMX). Conventional haloscope analyses search for a signal with a narrow bandwidth, as predicted for dark matter, whereas the CaB will be broad. We introduce a novel analysis strategy, which searches for a CaB induced daily modulation in the power measured by the haloscope.

The multi-mode acoustic gravitational wave experiment: MAGE.

The Multi-mode Acoustic Gravitational wave Experiment (MAGE) is a high frequency gravitational wave detection experiment. In its first stage, the experiment features two near-identical quartz bulk acoustic wave resonators that act as strain antennas with spectral sensitivity as low as 6.6 × 10 [strain]/[Formula: see text] in multiple narrow bands across MHz frequencies.

Active Electric Dipole Energy Sources: Transduction via Electric Scalar and Vector Potentials.

The creation of electromagnetic energy may be realised by engineering a device with a method of transduction, which allows an external energy source, such as mechanical, chemical, nuclear, etc., to be impressed into the electromagnetic system through a mechanism that enables the separation of opposite polarity charges. For example, a voltage generator, such as a triboelectric nanogenerator, enables the separation of charges through the transduction of mechanical energy, creating an active physical dipole in the static case, or an active Hertzian dipole in the time-dependent case.

Direct search for dark matter axions excluding ALP cogenesis in the 63- to 67-μeV range with the ORGAN experiment.

The standard model axion seesaw Higgs portal inflation (SMASH) model is a well-motivated, self-contained description of particle physics that predicts axion dark matter particles to exist within the mass range of 50 to 200 micro-electron volts. Scanning these masses requires an axion haloscope to operate under a constant magnetic field between 12 and 48 gigahertz. The ORGAN (Oscillating Resonant Group AxioN) experiment (in Perth, Australia) is a microwave cavity axion haloscope that aims to search the majority of the mass range predicted by the SMASH model.

Search for Invisible Axion Dark Matter in the 3.3-4.2 μeV Mass Range.

We report the results from a haloscope search for axion dark matter in the 3.3-4.2  μeV mass range.

Rare Events Detected with a Bulk Acoustic Wave High Frequency Gravitational Wave Antenna.

This work describes the operation of a high frequency gravitational wave detector based on a cryogenic bulk acoustic wave cavity and reports observation of rare events during 153 days of operation over two separate experimental runs (run 1 and run 2). In both run 1 and run 2, two modes were simultaneously monitored. Across both runs, the third overtone of the fast shear mode (3B) operating at 5.

Precision Multi-Mode Dielectric Characterization of a Crystalline Perovskite Enables Determination of the Temperature-Dependent Phase Transitions.

Simple perovskite crystals undergo structural phase transitions on cooling to low temperatures, which significantly change the material properties of the crystal. In this work, we rigorously characterize the temperature evolution of permittivity of a perovskite crystal as it undergoes phase transitions. In particular, we have undertaken precision measurements of a single crystal of Strontium Titanate from 294.

Erratum: Upconversion Loop Oscillator Axion Detection Experiment: A Precision Frequency Interferometric Axion Dark Matter Search with a Cylindrical Microwave Cavity [Phys. Rev. Lett. 126, 081803 (2021)].

This corrects the article DOI: 10.1103/PhysRevLett.126.

Upconversion Loop Oscillator Axion Detection Experiment: A Precision Frequency Interferometric Axion Dark Matter Search with a Cylindrical Microwave Cavity.

First experimental results from a room-temperature tabletop phase-sensitive axion haloscope experiment are presented. The technique exploits the axion-photon coupling between two photonic resonator oscillators excited in a single cavity, allowing low-mass axions to be upconverted to microwave frequencies, acting as a source of frequency modulation on the microwave carriers. This new pathway to axion detection has certain advantages over the traditional haloscope method, particularly in targeting axions below 1  μeV (240 MHz) in energy.

Searching for Scalar Dark Matter via Coupling to Fundamental Constants with Photonic, Atomic, and Mechanical Oscillators.

We present a way to search for light scalar dark matter (DM), seeking to exploit putative coupling between dark matter scalar fields and fundamental constants, by searching for frequency modulations in direct comparisons between frequency stable oscillators. Specifically we compare a cryogenic sapphire oscillator (CSO), hydrogen maser (HM) atomic oscillator, and a bulk acoustic wave quartz oscillator (OCXO). This work includes the first calculation of the dependence of acoustic oscillators on variations of the fundamental constants, and demonstration that they can be a sensitive tool for scalar DM experiments.

Point-to-point stabilized optical frequency transfer with active optics.

Timescale comparison between optical atomic clocks over ground-to-space and terrestrial free-space laser links will have enormous benefits for fundamental and applied sciences. However, atmospheric turbulence creates phase noise and beam wander that degrade the measurement precision. Here we report on phase-stabilized optical frequency transfer over a 265 m horizontal point-to-point free-space link between optical terminals with active tip-tilt mirrors to suppress beam wander, in a compact, human-portable set-up.

Predicting Alzheimer's conversion in mild cognitive impairment patients using longitudinal neuroimaging and clinical markers.

Patients with mild cognitive impairment (MCI) have a high risk for conversion to Alzheimer's disease (AD). Early diagnose of AD in MCI subjects could help to slow or halt the disease progression. Selecting a set of relevant markers from multimodal data to predict conversion from MCI to probable AD has become a challenging task.

Metagenome of a Bronchoalveolar Lavage Fluid Sample from a Confirmed COVID-19 Case in Quito, Ecuador, Obtained Using Oxford Nanopore MinION Technology.

We report the metagenome analysis of a bronchoalveolar lavage (BAL) fluid sample from a confirmed coronavirus disease 2019 (COVID-19) case in Quito, Ecuador. Sequencing was performed using MinION technology.

Phenomenology and geographical gradients of atmospheric deposition in southwestern Europe: Results from a multi-site monitoring network.

This article presents the results of atmospheric deposition from a 15-sites network which cover remote, agricultural, urban and industrial areas in the Iberian Peninsula and the Balearic Islands, with the aim of exploring geographical, climatic and natural vs anthropogenic gradients. Annual average fluxes of global deposition, discriminating insoluble (3,5-20,7 g m year) and soluble-inorganic (7,1-45,5 g m year) aerosols are discussed, seasonal patterns are regarded, and an attempt to estimate the impact of the main sources is presented. The wide range of atmospheric deposition fluxes (DF) regarding soluble (DF) and insoluble (DF) has been investigated taking into consideration the contribution from nearby to long-distance sources, such as African dust, or regional-to-nearby ones, which include agricultural dust in the Ebro Valley, industrial emissions at different parts, urban dust at all cities, or saline dust resuspension from a dissicated lake bed.

Genome sequencing of the first SARS-CoV-2 reported from patients with COVID-19 in Ecuador.

SARS-CoV-2, the etiological agent of COVID-19 was first described in Wuhan in December 2019 and has now spread globally. Ecuador was the second country in South America to report confirmed cases. The first case reported in Quito, the capital city of Ecuador, was a tourist who came from the Netherlands and presented symptoms on March 10th, 2020 (index case).

Longitudinal survival analysis and two-group comparison for predicting the progression of mild cognitive impairment to Alzheimer's disease.

Background: Longitudinal studies using structural magnetic resonance imaging (MRI) and neuropsychological measurements (NMs) allow a noninvasive means of following the subtle anatomical changes occurring during the evolution of AD.

New Method: This paper compared two approaches for the construction of longitudinal predictive models: a) two-group comparison between converter and nonconverter MCI subjects and b) longitudinal survival analysis. Predictive models combined MRI-based markers with NMs and included demographic and clinical information as covariates.

Divergent molecular and growth responses of young "Cabernet Sauvignon" () plants to simple and mixed infections with .

(GRSPaV) is one of the most widely distributed viruses; even so, little is known about its effect on . To provide new insights, the effects of single and mixed GRSPaV infections on the cultivar "Cabernet Sauvignon" were studied by evaluating growth parameters, such as measurements of the total plant length, the number and distance of internodes and the number of leaves per shoot. In addition, parameters relating to gas exchange, .

Early rise in central venous pressure during a spontaneous breathing trial: A promising test to identify patients at high risk of weaning failure?

Background: The spontaneous breathing trial (SBT) assesses the risk of weaning failure by evaluating some physiological responses to the massive venous return increase imposed by discontinuing positive pressure ventilation. This trial can be very demanding for some critically ill patients, inducing excessive physical and cardiovascular stress, including muscle fatigue, heart ischemia and eventually cardiac dysfunction. Extubation failure with emergency reintubation is a serious adverse consequence of a failed weaning process.

Combined Search for a Lorentz-Violating Force in Short-Range Gravity Varying as the Inverse Sixth Power of Distance.

Precision measurements of the inverse-square law via experiments on short-range gravity provide sensitive tests of Lorentz symmetry. A combined analysis of data from experiments at the Huazhong University of Science and Technology and Indiana University sets simultaneous limits on all 22 coefficients for Lorentz violation correcting the Newton force law as the inverse sixth power of distance. Results are consistent with no effect at the level of 10^{-12}  m^{4}.