Development and selection of candidate monoclonal antibodies for the detection of Clostridium botulinum neurotoxin serotype B light chain.

Botulinum neurotoxin, produced by the bacterium Clostridium botulinum, causes botulism, a severe, rapidly progressing, and potentially fatal condition. Swift detection of the toxin and timely administration of antitoxin antibodies are critical for effective treatment. The current standard for Botulinum toxin testing is the mouse lethality assay, but this method is time-consuming and requires live animals.

Comparing Visual Outcomes of KLEx, PRK, and LASIK Procedures in the Military Population.

Purpose: To assess the 6-month visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) as compared to laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in a military population at a Joint Warfighter Refractive Surgery Center.

Setting: Joint Warfighter Refractive Surgery Center (JWRSC), Lackland Air Force Base, San Antonio, TX.

Design: Retrospective Study.

Coupling hydroclimate-hydraulic-sedimentation models to estimate flood inundation and sediment transport during extreme flood events under a changing climate.

Extreme flood events are disastrous and can cause serious damages to society. Flood frequency obtained based on historical flow records may also be changing under future climate conditions. The associated flood inundation and environmental transport processes will also be affected.

Assessment of the effects of multiple extreme floods on flow and transport processes under competing flood protection and environmental management strategies.

Extreme floods are regarded as one of the most catastrophic natural hazards and can result in significant morphological changes induced by pronounced sediment erosion and deposition processes over the landscape. However, the effects of extreme floods of different return intervals on the floodplain and river channel morphological evolution with the associated sediment transport processes are not well explored. Furthermore, different basin management action plans, such as engineering structure modifications, may also greatly affect the flood inundation, sediment transport, solute transport and morphological processes within extreme flood events.