[Surgical treatment of diffuse toxic goiter associated with autoimmune thyroiditis].

An experience of the clinic with the surgical treatment of diffuse toxic goiter associated with autoimmune thyroiditis for the recent 16 years has been generalized based upon 258 observations. Long-term results followed in 73.6% of the patients show that an improved method of operation thought to be less radical gives good results.

[Diffuse toxic goiter associated with autoimmune thyroiditis].

A study of 190 patients with diffuse toxic goiter combined with autoimmune thyroiditis has revealed some clinical features: a torpid course and a solid-elastic consistency of the thyroid. In 37.4% of the cases autoimmune thyroiditis was combined with a severe form of thyrotoxicosis.

[Disorders of regional blood flow in diabetic angiopathy of the lower limbs and their clinical significance].

Radionuclide methods were used for the examination of 102 patients with diabetic angiopathies of lower extremities. Disturbed blood flow of the muscles was revealed in 100% of the cases, the main blood flow being damaged in 48.6% of the patients.

[Characteristics of microcirculation in patients with diabetic angiopathies].

The radionuclide technique was used to study regional microcirculation in 139 patients with diabetic angiopathies of the lower limbs. All the examined demonstrated impairment of the muscular bloodflow, that increased depending on the disease stage and diabetes mellitus standing. No differences were recorded in the degree of bloodflow impairment in the muscles of patients treated with sulfanilurea drugs and insulin.

[Differential diagnosis of hyperparathyroidism].

A great variety of clinical symptoms makes differential diagnosis of hyperparathyroidism difficult (only in 46.5% of patients sent to the clinic with the mentioned diagnosis was it confirmed). Complex clinical laboratory, and roentgenological examination of the patients permit to confirm or refute the diagnosis.

[Glucocorticoid and androgenic functions of the adrenal cortex and the state of the sympathetic-adrenal system in thyrotoxicosis with primary organic disease of the central nervous system].

In patients with thyrotoxicosis combined with primary affection of the central nervous system (CNS)-encephalitis, diencephalitis-there was revealed, like in common thyrotoxicosis, an increased production by the adrenal cortex of hydrocortisone, its intensified transformation and inactivation, reduced production of 17-ketosteroid chiefly due to the fall of dehydroepiandrosterone content, an increased urinary excretion of adrenaline and a decreased-of noradrenaline. The use of functional test with the ACTH administration demonstrated organic affection of the CNS to sharply aggravate the weakening and even the exhaustion of the functional reserves of the glomerular and the reticular zones of the adrenal cortex developing during thyrotoxicosis, and also the reserve possibilities of the sympathico-adrenal system. Direction of the changes in the 24-hour excretion of 17-OCS and corticosteriods was the same in the majority of cases.

[Surgery of thyrotoxicosis associated with diseases of the central nervous system].

Studies on 1432 thyrotoxicosis cases attracted the attention to a relatively high incidence (7.7%) of its association with damage to the central nervous system. 27 of 110 patients with combined type of thyrotoxicosis developed malignant exophthalmos.