Publications by authors named "Tizziani Benitez-Guerrero"
The entero-mammary pathway is a specialized route that selectively translocates bacteria to the newborn's gut, playing a crucial role in neonatal development. Previous studies report shared bacterial and archaeal taxa between human milk and neonatal intestine. However, the functional implications for neonatal development are not fully understood due to limited evidence.
View Article and Find Full Text PDFGestational diabetes (GD), pre-gestational diabetes (PD), and pre-eclampsia (PE) are morbidities affecting gestational health which have been associated with dysbiosis of the mother's gut microbiota. This study aimed to assess the extent of change in the gut microbiota diversity, short-chain fatty acids (SCFA) production, and fecal metabolites profile in a sample of Mexican women affected by these disorders. Fecal samples were collected from women with GD, PD, or PE in the third trimester of pregnancy, along with clinical and biochemical data.
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- Mammary gland secretory cells in humans produce milk rich in miRNAs, which are important for infant development and immune system maturation.
- This study aimed to compare the levels of specific immunoregulatory miRNAs in human colostrum and milk with those in infant milk formula.
- Results showed that these miRNAs are consistently present in human milk at higher levels than in formula, indicating their potential importance for infant health.
Coronavirus disease 2019 (COVID-19) is a disease produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and it is currently causing a catastrophic pandemic affecting humans worldwide. This disease has been lethal for approximately 3.12 million people around the world since January 2020.
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- *Methods involved collecting nasopharyngeal swabs from 133 mothers and 131 neonates, along with 140 colostrum samples, to check for SARS-CoV-2 using qPCR.
- *Results showed that 12.5% of asymptomatic pregnant women and 8.3% of neonates tested positive for SARS-CoV-2, indicating possible perinatal transmission, although no significant associations were found with maternal or newborn metadata.
Aims: Previous reports have demonstrated that alterations or reduced expression of Dystroglycan (Dg) complex (αDg and βDg subunits) are related to progression and severity of neoplastic solid tissues. Therefore we determined the expression pattern and subcellular distribution of Dg complex in Acute Myeloid Leukemia (AML) primary blasts (M1, M2, and M3 phenotypes), as well as HL-60 and Kasumi-1 leukemia cell lines. Additionally, we evaluated the relative expression of the main enzymes controlling α-Dg glycosylation to ascertain the post-translational modifications in the leukemia cell phenotype.
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