Publications by authors named "Tiziana Mulas"
Article Synopsis
- Histoplasmosis is a fungal infection that mainly affects people with weak immune systems, like those with HIV, especially in certain regions of Europe.
- A study looked at 78 articles and found 109 patients with this infection, mostly in Italy, France, and Spain, with an average age of 37.
- Most patients had a serious form of histoplasmosis, and treatments included antifungal medications, but about 24% of the patients sadly passed away. *
Hepatitis B Core antibody (HBcAb) positivity is the surrogate marker of hepatitis B occult infection. This condition is not a contraindication for switching to two-drug (2DR) antiretroviral therapy; however, the removal of tenofovir may contribute to poor control of HBV replication. A multicentre retrospective cohort study investigated the impact of HBcAb positivity on HIV control in patients switching to a 2DR with Lamivudine and Dolutegravir (3TC-DTG).
View Article and Find Full Text PDFBackground: Prosthetic joint infection (PJI) caused by represents a severe complication in orthopedic surgery. We report the case of a patient with chronic PJI from successfully treated with personalized phage therapy (PT) in combination with meropenem.
Methods: A 62-year-old woman was affected by a chronic right hip prosthesis infection caused by since 2016 .
Article Synopsis
- This study looked at how having certain antibodies (HBcAb) affects HIV treatment in patients who switched to a two-drug therapy with lamivudine.
- Out of 160 patients, those with HBcAb had a much lower chance of controlling their HIV compared to those without these antibodies.
- The study found that patients with HBcAb were more likely to have problems with their HIV levels coming back, especially after switching treatments.
Background: to evaluate whether prior SARS-CoV-2 infection affects side effects and specific antibody production after vaccination with BNT162b2. Methods: We included 1106 health care workers vaccinated with BNT162b2. We assessed whether prior SARS-CoV-2 infection affects the number and type of side effects and performed a nested case−control analysis comparing plasma levels of specific IgG titers between SARS-CoV-2-naïve and previously infected subjects after the first and the second vaccine doses.
View Article and Find Full Text PDFThe anti-HBc-positive/HBsAg-negative status is frequent in HIV-infection and correlates with poor survival. Here, by highly-sensitive assays, we evaluate cryptic HBV replication and factors correlated with its detection in 81 anti-HBc-positive/HBsAg-negative HIV-infected patients. Patients were treated for >12 months with HBV-active modern combined antiretroviral-therapy (cART) and had serum HBV-DNA < 20 IU/mL by commercial Real-Time PCR.
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