Fibrosarcomatous Dermatofibrosarcoma Protuberans With COL1A1-PDGFB Fusion in a 2-Year-Old Child: A Rare Occurrence With Spectrum of Histopathological Findings and Review of Literature.

Dermatofibrosarcoma protuberans (DFSP) is an intermediate-grade fibroblastic neoplasm commonly seen in young and middle-aged patients and rarely in pediatric patients. Fibrosarcomatous transformation is common in adults but extremely uncommon in children. Here, we present a case of a 2-year-old child who presented with a progressively enlarging subcutaneous mass in the knee.

Stress-relieving plant growth-promoting bacterial co-inoculation enhances nodulation and nitrogen uptake in black gram under nitrogen-free saline conditions.

Non-halophytic plants are highly susceptible to salt stress, but numerous studies have shown that halo-tolerant microorganisms can alleviate this stress by producing phytohormones and enhancing nutrient availability. This study aimed to identify and evaluate native microbial communities from salt-affected regions to boost black gram () resilience against salinity, while improving plant growth, nitrogen uptake, and nodulation in saline environments. Six soil samples were collected from a salt-affected region in eastern Uttar Pradesh, revealing high electrical conductivity (EC) and pH, along with low nutrient availability.

Yoga: As a Transformative Approach to Addressing Male Infertility and Enhancing Reproductive Health in Men: A Narrative Review.

Infertility presents multifaceted challenges that encompass both physical and emotional burdens. Yoga, as a comprehensive system of mind-body medicine, serves as an effective intervention for managing male factor infertility, a complex lifestyle disorder with significant psychosomatic elements. This review explores the transformative role of yoga in addressing both the emotional and physical dimensions of infertility.

Advances for Managing Pancreatic Cystic Lesions: Integrating Imaging and AI Innovations.

Pancreatic cystic lesions (PCLs) represent a spectrum of non-neoplasms and neoplasms with varying malignant potential, posing significant challenges in diagnosis and management. While some PCLs are precursors to pancreatic cancer, others remain benign, necessitating accurate differentiation for optimal patient care. Conventional approaches to PCL management rely heavily on radiographic imaging, and endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA), coupled with clinical and biochemical data.

Optimal design of tilt integral derivative controller for a boost converter based on swarm-inspired algorithms.

This article proposes a novel dual-loop control (DLC) method with a Tilt Integral Derivative (TID) Controller for output voltage regulation and inductor current regulation in a boost converter. The TID controller is designed with the aid of swarm inspired algorithms, particularly Artificial Bee Colony (ABC) and Salp Swarm Optimization (SSO). The TID Controller is a robust, and feedback type of controller and belongs to the family of fractional order controllers.

Therapeutic Bronchoscopic Interventions for Non Foreign-Body Removal Indications in Children.

Background: The indications for pediatric airway endoscopy are expanding and a variety of therapeutic interventions are feasible for central airway obstruction (CAO) and other central airway pathologies, apart from foreign body removal.

Methods: In this retrospective chart review from four centers, we describe the indications, procedures, outcomes, and complications of therapeutic bronchoscopic interventions in children for non foreign-body removal indications.

Results: A total of 72 children (mean age:140 [60.

Factors related to risk of recurrence and recurrence free survival in ameloblastoma of the Jaws: A single centre retrospective analysis.

Purpose: Ameloblastoma is a benign tumor originating from odontogenic epithelium with a global incidence of about 0.5 cases per million persons per year. The overall recurrence rate of ameloblastomas range from 55% -90%.

Evaluating cervical mucous inflammatory status as novel predictor for spontaneous onset of labour at term: A prospective observational study.

Background: The objective of this study was to explore the relationship between cervical inflammatory status at term gestation and spontaneous onset of labour. The was to search for a cost-effective, readily available, point of care test as predictor for spontaneous onset of labour (SPOL) at term.

Methods: This prospective observational cohort study was .

Epigenome-Wide and Methylation Risk Score Analysis of Body Mass Index Among People with HIV.

People with HIV (PWH) on antiretroviral therapy (ART) often gain weight, which increases their risk of type 2 diabetes and cardiovascular disease. The role of DNA methylation (DNAm) markers in obesity among PWH is understudied. This research explores the relationship between body mass index (BMI) and epigenetic patterns to better understand and manage obesity-related risks in PWH.

Perceived stigma among undergraduate medical students towards people with psychiatric illness: A cross sectional study.

Background: Over 450 million individuals worldwide suffer from mental illnesses, according to epidemiological data, making this one of the biggest problems facing modern medicine. People often react in a fairly discriminatory way to those with mental illness, and stigmatizing views toward those with mental illness are ubiquitous. In India, people who suffer from mental illness live with their families, and the stigma associated with mental illness has a significant impact on how effectively these people are treated over time by their families and communities.

Impact of psychological fear and media on infectious diseases induced by carriers.

To manage risks and mitigate the transmission of infectious diseases, individuals often adopt strategies aimed at reducing interpersonal contact by implementing precautionary measures within their daily routines. These behavioral adjustments reduce the disease transmission rates. In this study, we present a novel mathematical model delineating diseases induced by carriers, incorporating multifaceted factors, such as psychological fear, media impact, and sanitation interventions.

Self-supervised pre-trained neural network for quantum natural language processing.

Quantum computing models have propelled advances in many application domains. However, in the field of natural language processing (NLP), quantum computing models are limited in representation capacity due to the high linearity of the underlying quantum computing architecture. This work attempts to address this limitation by leveraging the concept of self-supervised pre-training, a paradigm that has been propelling the rocketing development of NLP, to increase the power of quantum NLP models on the representation level.

Investigating the psychometric properties of pathological concern questionnaire in Indian emerging adults.

Background: The Pathological Concern Questionnaire (PCQ) measures thoughts, emotions, and actions based on attitudes, including repression of personal needs and overinvestment in satisfaction of others' needs. The PCQ is widely used in the literature, but its psychometric properties are not well-established in the Indian population.

Aim: The current study aimed to examine the reliability and validity of PCQ among emerging adults in India.

design and discovery of pan coronavirus small molecule anti-virals targeting 3CL protease.

Coronaviruses (CoV), belonging to the family , were not considered dangerous pathogens until the outbreaks of SARS, MERS, and more recently, COVID-19. The coronaviruses causing these respective diseases/syndromes, SARS, MERS, and SARS-CoV2, share high sequence and structural similarities. COVID-19 continues to have a global impact on human health and the economy.

Machine Learning-based Prognostic Subgrouping of Glioblastoma: A Multi-center Study.

Background: Glioblastoma is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patient management, treatment planning, and clinical trial stratification.

Methods: We developed a highly reproducible, personalized prognostication and clinical subgrouping system using machine learning (ML) on routine clinical data, MRI, and molecular measures from 2,838 demographically diverse patients across 22 institutions and 3 continents. Patients were stratified into favorable, intermediate, and poor prognostic subgroups (I, II, III) using Kaplan-Meier analysis (Cox proportional model and hazard ratios [HR]).

Characterization of molecular interactions between HDAC7 and MEF2A.

Interactions of transcriptional corepressors such as histone deacetylase 7 (HDAC7), a class IIa HDAC, with myocyte enhancer factor-2 (MEF2) regulate MEF2 activity. Despite previous investigations exploring interactions between HDAC7 and MEF2, a detailed characterization of the HDAC7-MEF2 functional complex is still lacking. Herein, we first modeled the structure of the HDAC7-MEF2A complex and investigated the inter-protein interactions using all-atom molecular dynamics (MD) simulations.

An Annotated Checklist of Earthworms (Annelida: Clitellata: Oligochaeta) of Indo-Gangetic Plains of India.

A checklist of earthworm species hitherto known from Indo-Gangetic Plains of India is presented. In total, 98 species and subspecies are recorded, belonging to 33 genera spread over 9 families. Of these, 38 species are recognized as endemics and 34 as exotics.

Hybrid Source of Quantum Light for Generation of Frequency Tunable Fock States.

We propose a scheme for quantum-light generation in a nonlinear cavity hybridized with a two-level system and theoretically show that, when excited by a series of controlled pump pulses, the hybrid source generates Fock states with high probabilities, e.g., one- and two-photon states can be generated near on demand, and Fock states with up to seven photons with a probability above 50%.

Total gaseous mercury in Kathmandu, a South Asian metropolis: Temporal variations, sources apportionment and health risk assessment.

South Asia is a global hotspot of air pollution gaining attention due to its severe implications, in which atmospheric mercury (Hg) could cause detrimental health effects in metropolitan areas. In this study, first-time year-round (January - December 2019) mean total gaseous mercury (TGM) concentration at Kathmandu, Nepal - a sub-tropical city in South Asia was reported at 9.9 ± 10.

Quantum-inspired neural network with hierarchical entanglement embedding for matching.

Quantum-inspired neural networks (QNNs) have shown potential in capturing various non-classical phenomena in language understanding, e.g., the emgerent meaning of concept combinations, and represent a leap beyond conventional models in cognitive science.

EDDINet: Enhancing drug-drug interaction prediction via information flow and consensus constrained multi-graph contrastive learning.

Predicting drug-drug interactions (DDIs) is crucial for understanding and preventing adverse drug reactions (ADRs). However, most existing methods inadequately explore the interactive information between drugs in a self-supervised manner, limiting our comprehension of drug-drug associations. This paper introduces EDDINet: Enhancing Drug-Drug Interaction Prediction via Information Flow and Consensus-Constrained Multi-Graph Contrastive Learning for precise DDI prediction.