Biological Activities of Some Isoquinoline Alkaloids from Soy. Will.

Soy. Will. is a species belonging to the Papaveraceae family, being widespread in East-Central and Southern Europe.

In vitro Antileishmanial, Antitrypanosomal, and Anti-inflammatory-like Activity of Terminalia mollis Root Bark.

This study aims at determining the antitrypanosomal, antileishmanial, antioxidant, and anti-inflammatory-like activities of root crude extracts. The antitrypanosomal and antileishmanial activities on (strain 427) and promastigotes of (MHOM/BZ/84/BEL46) were evaluated . The methanolic root bark extract and standards were profiled by HPLC-PDA, and the majority of compounds identified using literature data.

Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta.

Objective: This study aims to evaluate the vasodilatory effect of Chenopodium ambrosioides on the isolated rat aorta, and to explore its mechanism of action.

Methods: The vasorelaxant effect and the mode of action of various extracts from the leaves of C. ambrosioides were evaluated on thoracic aortic rings isolated from Wistar rats.

Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract.

Objectives: The aim of the present study consisted in the isolation of flavonoids from the leaves of Bryonia alba L. and evaluation of their antioxidant activity and inhibition on peroxidase-catalysed reactions.

Methods: Flavonoids were isolated by preparative HPLC-DAD and their structures were elucidated by MS and NMR.

UMONS-TAICHI: A multimodal motion capture dataset of expertise in Taijiquan gestures.

In this article, we present a large 3D motion capture dataset of Taijiquan martial art gestures ( = 2200 samples) that includes 13 classes (relative to Taijiquan techniques) executed by 12 participants of various skill levels. Participants levels were ranked by three experts on a scale of [0-10]. The dataset was captured using two motion capture systems simultaneously: 1) Qualisys, a sophisticated optical motion capture system of 11 cameras that tracks 68 retroreflective markers at 179 Hz, and 2) Microsoft Kinect V2, a low-cost markerless time-of-flight depth sensor that tracks 25 locations of a person׳s skeleton at 30 Hz.

Robust and automatic motion-capture data recovery using soft skeleton constraints and model averaging.

Motion capture allows accurate recording of human motion, with applications in many fields, including entertainment, medicine, sports science and human computer interaction. A common difficulty with this technology is the occurrence of missing data, due to occlusions, or recording conditions. Various models have been proposed to estimate missing data.

Antihypertensive and vasorelaxant effects of aqueous extract of Artemisia campestris L. from Eastern Morocco.

Ethnopharmacological Relevance: Artemisia campestris L. (Asteraceae) has many traditional uses, among which treatment of diabetes and hypertension.

Aim Of The Study: This study was conducted in order to confirm the antihypertensive and hypotensive effects of A.

Antiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents.

Ethnopharmacological Relevance: Decoctions of the leaves of M. benthamianum Baill. are used by traditional healers in Guinea to treat malaria and this use was validated by a preliminary clinical assay.

Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo.

The aim of this study was to evaluate and compare the cellular antioxidant activities of Lantana montevidensis, Lippia multiflora, and Ocimum gratissimum leaves often consumed as herbal teas in a rural area of Bandundu severely affected by konzo, which is related to oxidative damage. Consequently, dietary supplements with proven antioxidant potentialities could be of real interest to promote in this area. Phytochemical screening by TLC and HPLC-DAD of extracts revealed the presence of verbascoside as a major phenolic compound.

Antiplasmodial activity of Heinsia crinita (Rubiaceae) and identification of new iridoids.

Ethnopharmacological Relevance: Heinsia crinita is used in traditional medicine for the treatment of febrile illness and erectile dysfunction. Its stem bark powder is found in some peripheral markets in the Democratic Republic of the Congo (DRC) as a remedy against malaria. Investigations were conducted on crude extracts of leaves, fruits and stem barks in view to validate their use and to determine which plant part possesses the best antiplasmodial properties.

Fingerprinting and validation of a LC-DAD method for the analysis of biflavanones in Garcinia kola-based antimalarial improved traditional medicines.

African populations use traditional medicines in their initial attempt to treat a range of diseases. Nevertheless, accurate knowledge of the composition of these drugs remains a challenge in terms of ensuring the health of population and in order to advance towards improved traditional medicines (ITMs). In this paper chromatographic methods were developed for qualitative and quantitative analyses of a per os antimalarial ITM containing Garcinia kola.

Head repositioning accuracy in patients with neck pain and asymptomatic subjects: concurrent validity, influence of motion speed, motion direction and target distance.

Background: Cervicocephalic kinesthetic deficiencies have been demonstrated in patients with chronic neck pain (NP). On the other hand, authors emphasized the use of different motion speeds for assessing functional impairment of the cervical spine.

Purpose: The objectives of this study were (1) to investigate the head repositioning accuracy in NP patients and control subjects and (2) to assess the influence of target distance, motion speed, motion direction and pain.

In vitro and in vivo antiplasmodial activity of three Rwandan medicinal plants and identification of their active compounds.

In our previous study, we reported the interesting in vitro antiplasmodial activity of some Rwandan plant extracts. This gave rise to the need for these extracts to also be evaluated in vivo and to identify the compounds responsible for their antiplasmodial activity. The aim of our study was, on the one hand, to evaluate the antiplasmodial activity in vivo and the safety of the selected Rwandan medicinal plants used in the treatment of malaria, with the objective of promoting the development of improved traditional medicines and, on the other hand, to identify the active ingredients in the plants.

Strychnobaillonine, an unsymmetrical bisindole alkaloid with an unprecedented skeleton from Strychnos icaja roots.

A reinvestigation of the roots of Strychnos icaja resulted in the isolation of a new bisindole alkaloid named strychnobaillonine (1) with original C-17-N-1' and C-23-C-17' junctions, in addition to sungucine, bisnordihydrotoxiferine, and strychnohexamine (2). Compound 1 showed potent activity against the chloroquine-sensitive 3D7 strain of Plasmodium falciparum in vitro with an IC50 value of 1.1 μM.

Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum.

Glaucium flavum is used in Algerian folk medicine to remove warts (benign tumors). Its local appellations are Cheqiq el-asfar and Qarn el-djedyane. We have recently reported the anti-tumoral activity of Glaucium flavum root alkaloid extract against human cancer cells, in vitro and in vivo.

Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells.

Glaucium flavum (G. flavum) is a plant from the Papaveraceae family native to Algeria where it is used in local traditional medicine to treat warts. G.

Unusual amino acids and monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a toxic plant from Rwanda.

In the course of our investigations on Umutambasha in order to identify its convulsant principles, small quantities of monofluoroacetate were observed in stem bark, leaves, and fruits of this plant newly identified as Dichapetalum michelsonii Hauman. Conclusive evidence for a monofluoroacetate presence came from its isolation from the freeze-dried extract of stem bark. Three free unusual amino acids, named N-methyl-α-alanine, N-methyl-β-alanine, and 2,7-diaminooctan-1,8-dioic acid, described for the first time in a plant, and known trigonelline were also isolated from the stem bark of D.

Dimeric bisindole alkaloids from the stem bark of Strychnos nux-vomica L.

Strychnos nux-vomica L. (Loganiaceae) is famous for its monomeric alkaloid content, such as strychnine, a convulsant poison. The stem bark of the tree is traditionally used to treat intermittent fever in South East Asia.

Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15-O-acetate as the main active compound.

Background: Natural products could play an important role in the challenge to discover new anti-malarial drugs. In a previous study, Dicoma tomentosa (Asteraceae) was selected for its promising anti-plasmodial activity after a preliminary screening of several plants traditionally used in Burkina Faso to treat malaria. The aim of the present study was to further investigate the anti-plasmodial properties of this plant and to isolate the active anti-plasmodial compounds.

Rotenoid content and in vitro acaricidal activity of Tephrosia vogelii leaf extract on the tick Rhipicephalus appendiculatus.

This study aimed to determine the rotenoid content of leaf extracts of the white (TVW) and purple (TVP) varieties of Tephrosia vogelii, both collected in North-Kivu Province, Democratic Republic of Congo and to evaluate their in vitro acaricidal efficacy on the tick Rhipicephalus appendiculatus. The high performance liquid chromatography analysis of rotenoid compounds from those extracts revealed that the contents of rotenone and deguelin were respectively higher in the leaves of TVW (0.044% and 1.

Polyphenol content and modulatory activities of some tropical dietary plant extracts on the oxidant activities of neutrophils and myeloperoxidase.

Young leaves of Manihot esculenta Crantz (Euphorbiaceae), Abelmoschus esculentus (Malvaceae), Hibiscus acetosella (Malvaceae) and Pteridium aquilinum (Dennstaedtiaceae) are currently consumed as green vegetables by peoples in sub-Saharan Africa, Latin America, Asia and their migrants living in Western Europe. Sub-Saharan peoples use Manihot, Abelmoschus and Hibiscus also in the folk medicine to alleviate fever and pain, in the treatment of conjunctivitis, rheumatism, hemorrhoid, abscesses, ..

Antioxidant and antiradical activities of Manihot esculenta Crantz (Euphorbiaceae) leaves and other selected tropical green vegetables investigated on lipoperoxidation and phorbol-12-myristate-13-acetate (PMA) activated monocytes.

Abelmoschus esculentus (Malvaceae), Hibiscus acetosella (Malvaceae), Manihot esculenta Crantz (Euphorbiaceae) and Pteridium aquilinum (Dennstaedtiaceae) leaves are currently consumed as vegetables by migrants from sub-Saharan Africa living in Western Europe and by the people in the origin countries, where these plants are also used in the folk medicine. Manihot leaves are also eaten in Latin America and some Asian countries. This work investigated the capacity of aqueous extracts prepared from those vegetables to inhibit the peroxidation of a linoleic acid emulsion.

[Fibromyalgia and physical therapy].

Fibromyalgia is a syndrome characterized by the existence of widespread musculoskeletal pain, present above and below the waist and the axial skeleton for a period of at least three months. Other symptoms are frequently present, intolerance to exercise, fatigue, trouble sleeping, morning stiffness, paresthesias, anxiety, headaches, etc. The exact etiology and pathophysiology of the disease are not clearly established.