Publications by authors named "Titouan Poquillon"
Article Synopsis
- Mitochondria are crucial for tissue health, stress responses, and disease monitoring, leading to a demand for technologies that can analyze their structure and function in various cells.
- The study introduces a new computerized method called MitoTouch that quickly and cost-effectively analyzes mitochondrial shape and network architecture from confocal images, offering over thirty analytical features.
- Using this tool, researchers identified a natural ingredient that helps protect mitochondria from damage caused by oxidative stress, while also demonstrating its effectiveness in distinguishing between different types of human cells, including cancerous ones.
Mitochondria are essential organelles that play crucial roles in cellular energy metabolism, calcium signaling and apoptosis. Their importance in tissue homeostasis and stress responses, combined to their ability to transition between various structural and functional states, make them excellent organelles for monitoring cellular health. Quantitative assessment of mitochondrial morphology can therefore provide valuable insights into environmentally-induced cell damage.
View Article and Find Full Text PDFFiber tractography enables the reconstruction of white matter fibers in 3 dimensions using data collected by diffusion tensor imaging, thereby helping to understand functional neuroanatomy. In a pre-operative context, it provides essential information on the trajectory of fiber bundles of medical interest, such as cranial nerves. However, the optimization of tractography parameters is a time-consuming process and requires expert neuroanatomical knowledge, making the use of tractography difficult in clinical routine.
View Article and Find Full Text PDF