Drug Chem Toxicol
September 2024
Knowledge and implications of atrazine in waters from rural areas in Nigeria remain diminutive. Meanwhile, recent findings have shown presence of atrazine residue in water bodies. Atrazine level in six communities (Mamu, Oru, Ilaporu, Awa, Ijebu Igbo, and Ago-Iwoye) of Ijebu North local government, Ogun State, Nigeria using 69 hand-dug wells (HDWs), 40 boreholes (BHs) and four streams are monitored.
View Article and Find Full Text PDFNo recognized study has been conducted in rural agricultural areas in Nigeria to monitor atrazine in drinking water and its potential health implications. Here, a total of 69 hand-dug wells (HDW), 40 boreholes (BH), and 4 streams were collected from the six (6) communities in Ijebu-North Local Government Area, Southwest Nigeria and analyzed for atrazine residue using gas chromatography-mass spectrometry (GC-MS). Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal routes in children and adults using the standard US EPA protocols.
View Article and Find Full Text PDFNo recognised study has been conducted to monitor atrazine residue in drinking water from rural agricultural areas in Nigeria and its potential health implications. In this ecotoxicological study, we monitored atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH) and 4 major streams from all the 6 communities (Ago-Iwoye, Ijebu-Igbo, Oru, Awa, Ilaporu and Mamu) in Ijebu North Local Government Area, Southwest Nigeria. Values of atrazine obtained were further used to evaluate the non-carcinogenic risk associated with ingestion and dermal contact in adults and children as well as neurotoxicity assessment.
View Article and Find Full Text PDFThere are no available data on the level of atrazine in drinking water from rural agricultural areas in Nigeria and its potential health implications. Here, we measured atrazine residue in 69 hand-dug wells (HDW), 40 boreholes (BH), and four major streams from the six communities (Ago-Iwoye, Ijebu-Igbo, Oru, Awa, Ilaporu, and Mamu) in Ijebu North Local Government Area, Southwest Nigeria. Values of atrazine obtained were further used for the evaluation of non-carcinogenic risk associated with ingestion and dermal contact in adults and children as well as reproductive toxicity evaluation.
View Article and Find Full Text PDFIntroduction: Scientists are considering the possibility of treating diabetes mellitus (DM) using a personalized approach in which various forms of the diseases will be treated based on the causal gene and its pathogenesis. To this end, scientists have identified mutations in certain genes as probable causes of Type 2 diabetes mellitus (T2DM) with diverse mechanisms.
Aim: This review was aimed at articulating already identified T2DM genes with their mechanisms of action and phenotypic presentations for the awareness of all stakeholders.