A retrospective review of lower extremity fracture care in patients with spinal cord injury.

Context/objective: To identify circumstances surrounding incident lower extremity fractures (ILEFs) in patients with spinal cord injury (SCI) and to describe the impact of these fractures on service needs and provision of pharmacological therapies for osteoporosis.

Design: Retrospective medical record review.

Setting: Four Veterans Affairs Medical Centers in the USA.

The association of anticonvulsant use with fractures in spinal cord injury.

Objective: The aim of this study was to determine whether anticonvulsants, including the benzodiazepine subclass, are associated with an increased risk for lower extremity fractures in male patients with spinal cord injury.

Design: All male patients with a history of a traumatic spinal cord injury of 2 yrs' duration or longer in the Veterans Affairs Spinal Cord Disease Registry from 2002 to 2007 were included. Incident lower extremity fractures during this period and anticonvulsant use were identified.

The association of opioid use with incident lower extremity fractures in spinal cord injury.

Objective: To determine the association between opioid use and lower extremity fracture risk in men with spinal cord injury (SCI).

Design: Retrospective cohort study.

Setting: Veterans Affairs Healthcare System.

Pharmacotherapy of systemic sclerosis.

Importance Of The Field: Systemic sclerosis (SSc) is an uncommon autoimmune disease with variable degrees of fibroproliferation in blood vessels and certain organs of the body. There is currently no cure. The purpose of this article is to review the current literature regarding pathogenesis and treatment of complications of SSc.