Publications by authors named "Tissera K"

Article Synopsis
  • The study examines the role of phase variation in the oipA gene of Helicobacter pylori, which is associated with IL-8 induction and gastric inflammation, in the context of H. pylori's overall virulence and potential links to gastric cancer.
  • Using two different strains, the research differentiates between natural and in vitro-induced phase variations of the oipA gene, discovering that while natural variations don’t significantly impact IL-8 induction or cell elongation, in vitro changes do show effects on cell morphology.
  • The findings highlight the complexity of genetic interactions influencing the virulence of H. pylori, suggesting that oipA phase variation plays a crucial, yet nuanced role in bacterial pathogenicity and warrants further investigation into
View Article and Find Full Text PDF
Article Synopsis
  • This study examined how living in rural versus urban areas and health professional shortages affected melanoma characteristics in North Carolina.
  • Researchers analyzed data from 807 melanoma patients treated at Duke University Health System between 2014 and 2020.
  • Findings revealed that rural patients were more likely to have thicker melanomas and were predominantly female, indicating a need for improved access to skin cancer screening and healthcare resources in underserved areas.
View Article and Find Full Text PDF

This study examined reliability and validity of the application to identify cricket ball landing position (line, length). Nine hundred and thirty-two deliveries were compared to 3D motion capture, the criterion measure, with 836 included in analysis (516 bowled (pace = 420, spin = 96), 320 Sidearm; 301 facing a batter). Agreement analysis indicated an intraclass correlation coefficient of >0.

View Article and Find Full Text PDF

The management of alopecia areata (AA) in pediatric patients poses unique challenges, particularly regarding treatment discussions and decision making involving both patients and their families. This commentary presents findings from unpublished research on treatment-discontinuation discussions between AA patients and their treating providers, shedding light on the hopes, expectations, and disappointments of individuals with severe AA. The study explored patient and guardian satisfaction with these discussions, emphasizing the importance of addressing psychosocial concerns, facilitating contact with support groups, and demonstrating empathy.

View Article and Find Full Text PDF

Congenital melanocytic nevi (CMN) carry an increased risk of melanoma and may be disfiguring, and consensus regarding treatment recommendations is lacking. While clinical monitoring is the standard of care, many caregivers are interested in its removal to prevent psychosocial burden or to decrease risk. Although melanoma can occur regardless of CMN removal, there are a variety of treatments that may offer improved cosmesis or local symptom control, including surgical excision, laser therapy, and other superficially destructive techniques.

View Article and Find Full Text PDF

Background: Psoriasis affects diverse racial and ethnic groups. In July 2021, the US Food and Drug Administration approved calcipotriene/betamethasone dipropionate (CAL/BDP) 0.005%/0.

View Article and Find Full Text PDF

Augmented feedback, including that provided using technology, can elicit multifaceted benefits on perceptual-motor learning and performance of sporting skills. However, current considerations of the applied value in supporting learning and teaching cricket skill is limited. This systematic review with meta-analysis aimed to understand the role and effectiveness of feedback-involved interventions on skill-based performance outcomes in cricket-related research.

View Article and Find Full Text PDF

Helicobacter pylori infection causes chronic inflammation in the stomach, which is linked to the development of gastric cancer. The anti-inflammatory and anticancer effects of a glycolysis inhibitor 2-deoxyglucose (2DG) and an antidiabetic medication metformin (Met) have gotten attention. Using a Mongolian gerbil animal model, we investigated H.

View Article and Find Full Text PDF

Objective: To determine the incidence and severity of progressive hearing loss in both ears in a population of longitudinally-tracked patients with unilateral hearing loss due to congenital cytomegalovirus (cCMV). By determining the natural history of unilateral hearing loss due to cCMV infection, we aim to facilitate therapeutic recommendations.

Study Design: Retrospective chart review.

View Article and Find Full Text PDF

The polymorphic bacterial oncoprotein, CagA shows geography-dependent variation in the C-terminal Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs; East-Asian H. pylori isolates carry the ABD type while Western isolates carry the ABC type. In Western isolates, the EPIYA-C motif is sometimes found in multi-copy and this genotype is associated with disease severity.

View Article and Find Full Text PDF

Background And Purpose: Vestibular aqueduct measurements in the 45° oblique (Pöschl) plane provide a reliable depiction of the vestibular aqueduct; however, adoption among clinicians attempting to counsel patients has been limited due to the lack of correlation with audiologic measures. This study aimed to determine the correlation between midpoint vestibular aqueduct measurements in the Pöschl plane in patients with an enlarged vestibular aqueduct with repeat audiologic measures.

Materials And Methods: Two radiologists independently measured the midpoint vestibular aqueduct diameter in the Pöschl plane reformatted from CT images in 54 pediatric patients (77 ears; mean age at first audiogram, 5 years) with an enlarged vestibular aqueduct.

View Article and Find Full Text PDF

Poor language development in patients with sensorineural hearing loss (SNHL) may be related to an auditory deficit and/or other neurologic condition that influences the ability to communicate. A retrospective chart review of children (mean age = 4.0 years) with congenital, bilateral SNHL was performed to assess for linguistic and nonlinguistic neurodevelopmental differences between those who were language-impaired (LI) versus non-language-impaired (NLI).

View Article and Find Full Text PDF

Clinical registries have proven beneficial by providing a resource to address research questions, monitor care, and identify suitable subjects for clinical studies. Despite a well-organized registry, population is often low because of the human capital required. The increasing prevalence of electronic medical health records provides the opportunity to integrate registry compilation into routine patient encounters.

View Article and Find Full Text PDF

Infection with CagA+ Helicobacter pylori strains is linked to an increased risk for gastric diseases, including gastric cancer. Recent evidence indicates that dynamic expansion and contraction of cagA copy number may serve as a novel mechanism to enhance disease development. Herein, comparative genomic analysis divided hpEurope into two groups: hpEurope/type-A and type-B.

View Article and Find Full Text PDF

Tissera, KM, Naughton, GA, Gabbett, TJ, Krause, LM, Moresi, MP, and Benson, AC. Sex differences in physical fitness characteristics and match-play demands in adolescent netball: Should male and female adolescents co-compete in netball? J Strength Cond Res 33(3): 846-856, 2019-Sports participation offers multifaceted benefits, especially during adolescence. However, policies relating to male and female adolescents co-competing in team sports can be prohibitive and lack an evidence base.

View Article and Find Full Text PDF

Background: Infections with multi drug resistant (MDR) organisms are a major problem in intensive care units (ICUs). Proper infection control procedures are mandatory to combat the spread of resistant organisms within ICUs. Well stablished surveillance programmes will enhance the adherence of the staff to infection control protocols.

View Article and Find Full Text PDF