Synthesis and evaluation of novel almazole D analogs as anticancer agents.

Novel almazole D-amide conjugates, esters, and N-alkylated analogs were synthesized and investigated for their anticancer activity against seven cancer cell lines. Among the series, compounds 5g and 5m showed significant anticancer activities against multiple cell lines with moderate selectivity indices. Compound 5g had IC values of 5.

Crosslinked enzyme aggregates (CLEA) of phytase with soymilk proteins.

Crosslinked Enzyme Aggregates (CLEA) of phytase (E.C. 3.