Characteristics of temper tantrums in 1-6-year-old children and impact on caregivers.

Background: Temper tantrums are common behavioral difficulties in children. Although they are generally considered a normal part of development, certain characteristics-such as aggression, prolonged duration, and frequent occurrences-have been linked to psychological issues and can negatively impact both the child and their caregivers.

Purpose: To study the prevalence and characteristics of temper tantrums in children aged 1-6 years at daycare and in kindergarten in Thailand as well as the impact of problematic and non-problematic tantrums on their caregivers' emotional well-being.

Attention-deficit/hyperactive-impulsive disorder symptoms among grade 1 students with reading disorder in Thailand.

Background: Reading disorder is the most common comorbid condition with attention-deficit/hyperactive-impulsive disorder (ADHD) in school-aged children.

Purpose: This study compared symptoms of ADHD among children in grade 1 at risk of reading disorder with children not at risk.

Methods: This cross-sectional study included 703 students in grade 1 aged 6-8 years from 8 schools in Pathumthani Province, Thailand, in 2019.

Chromosomal microarray analysis in a cohort of underrepresented population identifies SERINC2 as a novel candidate gene for autism spectrum disorder.

Chromosomal microarray (CMA) is now recognized as the first-tier genetic test for detection of copy number variations (CNVs) in patients with autism spectrum disorder (ASD). The aims of this study were to identify known and novel ASD associated-CNVs and to evaluate the diagnostic yield of CMA in Thai patients with ASD. The Infinium CytoSNP-850K BeadChip was used to detect CNVs in 114 Thai patients comprised of 68 retrospective ASD patients (group 1) with the use of CMA as a second line test and 46 prospective ASD and developmental delay patients (group 2) with the use of CMA as the first-tier test.

Parent Evaluation of Developmental Status (PEDS) in screening: The Thai experience.

Background: Parent Evaluation of Developmental Status (PEDS) is a feasible developmental screening tool but it is not commonly used in Thailand. To examine the potential of PEDS as a screening tool, PEDS was implemented in well-child visits to identify the prevalence of developmental problems, characteristic parental concerns and comments, and to compare it with pediatrician developmental evaluation using Parent Evaluation of Developmental Status: Developmental Milestones, assessment level (PEDS: DM-AL).

Methods: Participants were 266 children at the 9, 18 and 30 month health checkups as well as their parents.

A new structured interview for children with autism spectrum disorder based on the DSM-IV.

Background: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder in children. The clinical spectrum of ASD includes autism, childhood disintegrative disorder Asperger syndrome and pervasive developmental disorder not otherwise specified (PDD-NOS). Although the DSM-IVcriteria are well acceptedforASD diagnosis, there are some known limitations for clinicians.

A case with a ring chromosome 13 in a cohort of 203 children with non-syndromic autism and review of the cytogenetic literature.

Autistic spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairments of social interaction, communication and restricted, repetitive and stereotyped patterns of behavior, interests and activities. Frequencies of chromosomal abnormalities in cohorts of individuals with ASD varying between 1.2 and 28.

Mutation screening of the neurexin 1 gene in thai patients with intellectual disability and autism spectrum disorder.

Aim: Neurexin 1 has two major protein isoforms using alternative promoters, coding for the alpha-neurexin 1 (α-NRXN1) and beta-neurexin 1 (β-NRXN1) genes. This study is to explore the possibility that variants of the NRXN1 gene predispose to intellectual disability (ID) and autism spectrum disorder (ASD).

Methods: The coding regions in 24 exons and exon-intron boundaries of the NRXN1 gene were investigated in 115 Thai patients with ID and ASD by direct DNA sequencing.

Effects of mirror neurons stimulation on motor skill rehabilitation in children with cerebral palsy: a clinical trial.

Objective: The authors aimed to compare the motor function measured by Gross Motor Function Measure (GMFM-66) between mirror neurons stimulation based VCD program at home and conventional physical therapy in children with cerebral palsy for two months.

Material And Method: A randomized controlled trial was performed with thirty children with spastic diplegia aged 2-10 years in Thammasat university hospital and Rajanukul institue. They were randomly assigned to receive either the mirror neurons stimulation based VCD program practice at home (experimental group) or the conventional physical therapy (control group) for two months.

Epidemiology of enuresis among school-age children in Thailand.

Enuresis is a very common developmental problem in young children. The aims of this study were to estimate the prevalence of enuresis in school-age children, to determine the factors associated with nocturnal enuresis, and to evaluate the parental strategies for managing enuresis. A randomly selected cross-sectional population-based study was conducted in eight elementary schools in Bangkok, Thailand.